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Sunil Yeruva
Researcher at Ludwig Maximilian University of Munich
Publications - 43
Citations - 1097
Sunil Yeruva is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Chemistry & Desmosome. The author has an hindex of 15, co-authored 30 publications receiving 858 citations. Previous affiliations of Sunil Yeruva include University of Chicago & University of Göttingen.
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Journal ArticleDOI
IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance
Pei-Yun Tsai,Bingkun Zhang,Bingkun Zhang,Wei-Qi He,Wei-Qi He,Juan Min Zha,Juan Min Zha,Matthew A. Odenwald,Gurminder Singh,Gurminder Singh,Atsushi Tamura,Le Shen,Anne Sailer,Sunil Yeruva,Sunil Yeruva,Wei-Ting Kuo,Yang Xin Fu,Yang Xin Fu,Sachiko Tsukita,Jerrold R. Turner,Jerrold R. Turner +20 more
TL;DR: Infecting mice with the attaching and effacing bacteria Citrobacter rodentium defined the mechanisms and contributions of diarrhea and intestinal barrier loss to host defense and demonstrated that claudin-2-mediated protection is the result of enhanced water efflux.
Journal ArticleDOI
Lysophosphatidic Acid Stimulates the Intestinal Brush Border Na+/H+ Exchanger 3 and Fluid Absorption via LPA5 and NHERF2
Songbai Lin,Sunil Yeruva,Peijian He,Anurag Kumar Singh,Huanchun Zhang,Mingmin Chen,Georg Lamprecht,Hugo R. de Jonge,Ming Tse,Mark Donowitz,Boris M. Hogema,Jerold Chun,Ursula Seidler,Chang-Hyon Yun +13 more
TL;DR: LPA is a potent stimulant of NHE3 and fluid absorption in the intestine, signaling through LPA(5), which might be useful in the treatment of certain diarrheal diseases.
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NF-κB-dependent synergistic regulation of CXCL10 gene expression by IL-1β and IFN-γ in human intestinal epithelial cell lines
TL;DR: It is demonstrated that in colonic epithelial cells, IL-1β alone and/or in synergism with IFN-γ may play a major role in the induction of CXCL10.
Journal ArticleDOI
Loss of downregulated in adenoma (DRA) impairs mucosal HCO3(-) secretion in murine ileocolonic inflammation.
Fang Xiao,M Juric,Junhua Li,Junhua Li,Brigitte Riederer,Sunil Yeruva,Anurag Kumar Singh,Lifei Zheng,Lifei Zheng,Silke Glage,George Kollias,Pradeep K. Dudeja,De An Tian,Gang Xu,Jinxia Zhu,Oliver Bachmann,Ursula Seidler +16 more
TL;DR: Even mild ileocolonic inflammation may result in a decrease of epithelial HCOSymbol secretion, which may contribute to alterations in surface pH, intestinal flora, and mucus barrier properties.
Journal ArticleDOI
New therapeutic targets in ulcerative colitis: The importance of ion transporters in the human colon
Klaudia Farkas,Sunil Yeruva,Zoltán Rakonczay,Lisa Ludolph,Tamás Molnár,Ferenc Nagy,Zoltán Szepes,Andrea Schnúr,Tibor Wittmann,Jessica Hubricht,Brigitte Riederer,Viktória Venglovecz,György Lázár,Marianna Kiraly,Ákos Zsembery,Gábor Varga,Ursula Seidler,Péter Hegyi +17 more
TL;DR: Data collected from colonic crypts showed that the activities of electroneutral (via NHE3) and the electrogenic Na+ absorption (via ENaC) are in inverse ratio to each other in the proximal and distal colon.