S
Susan E. Wert
Researcher at Cincinnati Children's Hospital Medical Center
Publications - 78
Citations - 9447
Susan E. Wert is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Lung & ABCA3. The author has an hindex of 47, co-authored 78 publications receiving 8748 citations. Previous affiliations of Susan E. Wert include University of Cincinnati & University of Cincinnati Academic Health Center.
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Journal ArticleDOI
A Mutation in the Surfactant Protein C Gene Associated with Familial Interstitial Lung Disease
Lawrence M. Nogee,Alston E. Dunbar,Susan E. Wert,Frederic B. Askin,Aaron Hamvas,Jeffrey A. Whitsett +5 more
TL;DR: The lungs in patients with chronic pneumonitis of infancy are characterized by interstitial thickening with mesenchymal cells, rather than by an inflammatory infiltrate, and an alveolar infiltrate.
Journal ArticleDOI
ABCA3 gene mutations in newborns with fatal surfactant deficiency.
Sergey Shulenin,Lawrence M. Nogee,Tarmo Annilo,Susan E. Wert,Jeffrey A. Whitsett,Michael Dean +5 more
TL;DR: Mutation of the ABCA3 gene causes fatal surfactant deficiency in newborns and is critical for the proper formation of lamellar bodies and surfactan function and may also be important for lung function in other pulmonary diseases.
Journal ArticleDOI
Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.
TL;DR: Tissue surveys of transgene expression indicated low levels of activity in the lung, and analyses via the polymerase chain reaction confirmed the presence of the endogenous alpha-MHC gene transcripts in this tissue.
Journal ArticleDOI
Early restriction of peripheral and proximal cell lineages during formation of the lung.
TL;DR: Early restriction of endodermal progenitor cells forming peripheral as compared with proximal airways is demonstrated, distinct cell lineages in conducting airways are identified, and a system for conditional gene addition or deletion is useful for the study of lung morphogenesis and gene function in vivo.
Journal ArticleDOI
Diffuse lung disease in young children: application of a novel classification scheme.
Gail H. Deutsch,Lisa R. Young,Robin R. Deterding,Leland L. Fan,Sharon D. Dell,Judy A. Bean,Alan S. Brody,Lawrence M. Nogee,Bruce C. Trapnell,Claire Langston,Eric A. Albright,Frederic B. Askin,Peter B. Baker,Pauline M. Chou,Carlyne M. Cool,Susan Coventry,Ernest Cutz,Mary M. Davis,Megan K. Dishop,Csaba Galambos,Kathleen Patterson,William D. Travis,Susan E. Wert,Frances V. White +23 more
TL;DR: This retrospective cohort study identifies a diverse spectrum of lung disorders, largely unique to young children, that will enhance accurate description and diagnosis of these disorders.