S
Susan Solliday Rich
Researcher at Baylor College of Medicine
Publications - 43
Citations - 3196
Susan Solliday Rich is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: T cell & Lymphocyte. The author has an hindex of 20, co-authored 43 publications receiving 3168 citations. Previous affiliations of Susan Solliday Rich include Mayo Clinic & United States Department of Veterans Affairs.
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Journal ArticleDOI
Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1
James E. Sligh,Christie M. Ballantyne,Susan Solliday Rich,Hal K. Hawkins,C. W. Smith,Allan Bradley,Arthur L. Beaudet +6 more
TL;DR: In this article, gene targeting was used to produce mice deficient in intercellular adhesion molecule 1 (ICAM-1) or CD54, an immunoglobulin-like cell adhesion molecules that binds beta 2 integrins.
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pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells.
TL;DR: Fyn- thymocytes were impaired at a late stage of maturation and showed limited clonal deletion to the Mls-1a self-super-antigen but not to staphylococcal enterotoxin A, implicate fyn as a critical component in TCR signaling in thymocyte and, potentially, in the process that determines T cell repertoire in the adult mouse.
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Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice
Uwe Rudolph,Milton J. Finegold,Susan Solliday Rich,Gregory R. Harriman,Yogambal Srinivasan,Philippe Brabet,Philippe Brabet,Guylain Boulay,Guylain Boulay,Allan Bradley,Lutz Birnbaumer +10 more
TL;DR: Gαi2–deficient mice display growth retardation and develop a lethal diffuse colitis with clinical and histopathological features closely resembling ulcerative colitis in humans, including the development of adenocarcinoma of the colon.
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Spontaneous Skin Ulceration and Defective T Cell Function in CD18 Null Mice
Karin Scharffetter-Kochanek,Karin Scharffetter-Kochanek,Huifang Lu,Keith E. Norman,Nicole van Nood,Flor M. Munoz,Stephan Grabbe,Mark J. McArthur,Isabel Lorenzo,Isabel Lorenzo,Sheldon L. Kaplan,Klaus Ley,C. Wayne Smith,Charles A. Montgomery,Susan Solliday Rich,Arthur L. Beaudet,Arthur L. Beaudet +16 more
TL;DR: A severe defect in T cell proliferation was found in the CD18 null mice when T cell receptors were stimulated either by staphylococcal enterotoxin A or by major histocompatibility complex alloantigens demonstrating a greater role of CD11/CD18 integrins in Tcell responses than previously documented.
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Combination gene therapy for liver metastasis of colon carcinoma in vivo
S H Chen,Xinpu Chen,Yibin Wang,Ken-ichiro Kosai,Milton J. Finegold,Susan Solliday Rich,Savio L. C. Woo +6 more
TL;DR: The results suggest that combination suicide and cytokine gene therapy in vivo can be a powerful approach for treatment of metastatic colon carcinoma in the liver.