M
Mark J. McArthur
Researcher at University of Texas MD Anderson Cancer Center
Publications - 44
Citations - 3840
Mark J. McArthur is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Carcinogenesis & Neocortex. The author has an hindex of 25, co-authored 44 publications receiving 3394 citations. Previous affiliations of Mark J. McArthur include Georgia State University & Texas A&M University.
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Journal ArticleDOI
Prolonged myelination in human neocortical evolution
Daniel J. Miller,Tetyana Duka,Cheryl D. Stimpson,Steven J. Schapiro,Wallace B. Baze,Mark J. McArthur,Archibald J. Fobbs,André M. M. Sousa,André M. M. Sousa,Nenad Sestan,Derek E. Wildman,Leonard Lipovich,Christopher W. Kuzawa,Patrick R. Hof,Chet C. Sherwood +14 more
TL;DR: Comparisons between chimpanzees and humans suggest that the human-specific shift in the timing of cortical maturation during adolescence may have implications for vulnerability to certain psychiatric disorders.
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Cellular uptake and intracellular trafficking of long chain fatty acids.
Mark J. McArthur,Barbara P. Atshaves,Andrey Frolov,William D. Foxworth,Ann B. Kier,Friedhelm Schroeder +5 more
TL;DR: The emerging picture is that the cell has multiple, overlapping mechanisms that assure adequate uptake and directed intracellular movement of LCFA required for maintenance of physiological functions.
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Spontaneous Skin Ulceration and Defective T Cell Function in CD18 Null Mice
Karin Scharffetter-Kochanek,Karin Scharffetter-Kochanek,Huifang Lu,Keith E. Norman,Nicole van Nood,Flor M. Munoz,Stephan Grabbe,Mark J. McArthur,Isabel Lorenzo,Isabel Lorenzo,Sheldon L. Kaplan,Klaus Ley,C. Wayne Smith,Charles A. Montgomery,Susan Solliday Rich,Arthur L. Beaudet,Arthur L. Beaudet +16 more
TL;DR: A severe defect in T cell proliferation was found in the CD18 null mice when T cell receptors were stimulated either by staphylococcal enterotoxin A or by major histocompatibility complex alloantigens demonstrating a greater role of CD11/CD18 integrins in Tcell responses than previously documented.
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Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression
Guocan Wang,Xin Lu,Prasenjit Dey,Pingna Deng,Chia Chin Wu,Shan Jiang,Zhuangna Fang,Kun Zhao,Ramakrishna Konaparthi,Sujun Hua,Jianhua Zhang,Elsa M. Li-Ning-Tapia,Avnish Kapoor,Chang-Jiun Wu,Neelay Bhaskar Patel,Zhenglin Guo,Vandhana Ramamoorthy,Trang N. Tieu,Timothy P. Heffernan,Di Zhao,Xiaoying Shang,Sunada Khadka,Pingping Hou,Baoli Hu,Eun Jung Jin,Wantong Yao,Xiaolu Pan,Zhihu Ding,Yanxia Shi,Liren Li,Qing Chang,Patricia Troncoso,Christopher J. Logothetis,Mark J. McArthur,Lynda Chin,Y. Alan Wang,Ronald A. DePinho +36 more
TL;DR: A critical role of MDSCs in prostate tumor progression is demonstrated and a cancer cell nonautonomous function of the Hippo-YAP pathway in regulation of CXCL5, a ligand for CXCR2-expressing M DSCs is discovered.
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Genetic background alters the spectrum of tumors that develop in p53-deficient mice.
TL;DR: It appears that loss of p53 may accelerate a prior tumor predisposition and that genetic background can play a role in mediating both the rate and spectrum of tumor development in these mice.