S
Susanne V. Allander
Researcher at Karolinska Institutet
Publications - 9
Citations - 373
Susanne V. Allander is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Gene & Binding protein. The author has an hindex of 9, co-authored 9 publications receiving 368 citations.
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Glucocorticoids and Insulin Regulate Expression of the Human Gene for Insulin-like Growth Factor-binding Protein-1 through Proximal Promoter Elements* (Received for publication, February 1, 1994, and in revised form, September 1, 1994)
TL;DR: In this article, the first 1205 base pairs (BP) of the hIGFBP-1 promoter were constructed and transiently transfected with human hepatoma cells.
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Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization.
Mattias Berglund,Gunilla Enblad,Emma Flordal,Weng-Onn Lui,Carin Backlin,Ulf Thunberg,Christer Sundström,Göran Roos,Susanne V. Allander,Martin Erlanson,Richard Rosenquist,Catharina Larsson,Svetlana Lagercrantz +12 more
TL;DR: The distribution of CGH alterations support the idea of a progression of genetic events where loss of 8p and 9p and gain of 3q, 13q, and 18q would represent relatively early events because they were distributed in tumors with only two abnormalities.
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Characterization of the chromosomal gene and promoter for human insulin-like growth factor binding protein-5.
Susanne V. Allander,Catharina Larsson,Ewa Ehrenborg,A. Suwanichkul,G. Weber,S.L. Morris,Svetlana Bajalica,M.C. Kiefer,Holger Luthman,D.R. Powell +9 more
TL;DR: To better understand the regulation of insulin-like growth factor binding protein-5 (IGFBP-5) expression, cloned the IGF BP-5 gene from human genomic libraries and identified a region in the 5' flanking sequence which functions as a promoter.
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Hepatic nuclear factor 3 and high mobility group I/Y proteins bind the insulin response element of the insulin-like growth factor-binding protein-1 promoter.
Susanne V. Allander,Susan K. Durham,Ann O. Scheimann,Richard M. Wasserman,Adisak Suwanichkul,David R. Powell +5 more
TL;DR: The insulin response element (IRE) of the human insulin-like growth factor-binding protein-1 (IGFBP-1) promoter contains a palindrome of the T(A/G)TTT sequence crucial to hormonal regulation of many genes.
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Conservation of IGFBP structure during evolution: Cloning of chicken insulin-like growth factor binding protein-5
TL;DR: The hypothesis that IGFBPs are ancient proteins is supported by the reported detection of IGFBP activity in serum from the Agnathan species, Geotria australis, a primitive vertebrate, and the conservation of IGF BP-5 primary structure across vertebrate species suggests maintenance of important functions during evolution.