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Richard Rosenquist
Researcher at Karolinska Institutet
Publications - 383
Citations - 17000
Richard Rosenquist is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Chronic lymphocytic leukemia & IGHV@. The author has an hindex of 65, co-authored 353 publications receiving 15085 citations. Previous affiliations of Richard Rosenquist include Umeå University & Uppsala University.
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Journal ArticleDOI
Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
Eva Baecklund,Anastasia Iliadou,Johan Askling,Anders Ekbom,Anders Ekbom,Carin Backlin,Fredrik Granath,Anca I. Catrina,Richard Rosenquist,Nils Feltelius,Christer Sundström,Lars Klareskog +11 more
TL;DR: Risk of lymphoma is substantially increased in a subset of patients with RA, those with very severe disease, and high inflammatory activity, rather than its treatment, is a major risk determinant.
Journal ArticleDOI
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk
Fergus J. Couch,Xianshu Wang,Lesley McGuffog,Andy C. H. Lee,Curtis Olswold,Karoline Kuchenbaecker,Penny Soucy,Zachary S. Fredericksen,Daniel Barrowdale,Joe Dennis,Mia M. Gaudet,Ed Dicks,Matthew L. Kosel,Sue Healey,Olga M. Sinilnikova,Adam M. Lee,Francois Bacot,Daniel Vincent,Frans B. L. Hogervorst,Susan Peock,Dominique Stoppa-Lyonnet,Anna Jakubowska,Paolo Radice,Rita K. Schmutzler,Susan M. Domchek,Marion Piedmonte,Christian F. Singer,Eitan Friedman,Mads Thomassen,Thomas Hansen,Susan L. Neuhausen,Csilla Szabo,Ignacio Blanco,Mark H. Greene,Beth Y. Karlan,Judy Garber,Catherine M. Phelan,Jeffrey N. Weitzel,Marco Montagna,Edith Olah,Irene L. Andrulis,Andrew K. Godwin,Drakoulis Yannoukakos,David E. Goldgar,Trinidad Caldés,Heli Nevanlinna,Ana Osorio,Mary Beth Terry,Mary B. Daly,Elizabeth J. van Rensburg,Ute Hamann,Susan J. Ramus,Amanda E. Toland,Maria A. Caligo,Olufunmilayo I. Olopade,Nadine Tung,Kathleen Claes,Mary S. Beattie,Melissa C. Southey,Evgeny N. Imyanitov,Marc Tischkowitz,Ramunas Janavicius,Esther M. John,Ava Kwong,Orland Diez,Judith Balmaña,Rosa B. Barkardottir,Banu Arun,Gad Rennert,Soo Hwang Teo,Patricia A. Ganz,Ian G. Campbell,Annemarie H. van der Hout,Carolien H.M. van Deurzen,Caroline Seynaeve,Encarna B. Gomez Garcia,Flora E. van Leeuwen,Hanne Meijers-Heijboer,Johannes J. P. Gille,Margreet G. E. M. Ausems,Marinus J. Blok,Marjolijn J. L. Ligtenberg,Matti A. Rookus,Peter Devilee,Senno Verhoef,Theo A. M. van Os,Juul T. Wijnen,Debra Frost,Steve Ellis,Elena Fineberg,Radka Platte,D. Gareth Evans,Louise Izatt,Rosalind A. Eeles,Julian Adlard,Diana Eccles,Jackie Cook,Carole Brewer,Fiona Douglas,Shirley Hodgson,Patrick J. Morrison,Lucy Side,Alan Donaldson,C. E. Houghton,Mark T. Rogers,Huw Dorkins,Jacqueline Eason,Helen Gregory,Emma McCann,Alex Murray,Alain Calender,Agnès Hardouin,Pascaline Berthet,Capucine Delnatte,Catherine Noguès,Christine Lasset,Claude Houdayer,Dominique Leroux,Etienne Rouleau,Fabienne Prieur,Francesca Damiola,Hagay Sobol,Isabelle Coupier,Laurence Venat-Bouvet,Laurent Castera,Marion Gauthier-Villars,Mélanie Léoné,Pascal Pujol,Sylvie Mazoyer,Yves-Jean Bignon,Elżbieta Złowocka-Perłowska,Jacek Gronwald,Jan Lubinski,Katarzyna Durda,Katarzyna Jaworska,Tomasz Huzarski,Amanda B. Spurdle,Alessandra Viel,Bernard Peissel,Bernardo Bonanni,Giulia Melloni,Laura Ottini,Laura Papi,Liliana Varesco,Maria Grazia Tibiletti,Paolo Peterlongo,Sara Volorio,Siranoush Manoukian,Valeria Pensotti,Norbert Arnold,Christoph Engel,Helmut Deissler,Dorothea Gadzicki,Andrea Gehrig,Karin Kast,Kerstin Rhiem,Alfons Meindl,Dieter Niederacher,Nina Ditsch,Hansjoerg Plendl,Sabine Preisler-Adams,Stefanie Engert,Christian Sutter,Raymonda Varon-Mateeva,Barbara Wappenschmidt,Bernhard H. F. Weber,Brita Arver,Marie Stenmark-Askmalm,Niklas Loman,Richard Rosenquist,Zakaria Einbeigi,Katherine L. Nathanson,Timothy R. Rebbeck,Stephanie V. Blank,David E. Cohn,Gustavo C. Rodriguez,Laurie Small,Michael Friedlander,Victoria L. Bae-Jump,Anneliese Fink-Retter,Christine Rappaport,Daphne Gschwantler-Kaulich,Georg Pfeiler,Muy-Kheng Tea,Noralane M. Lindor,Bella Kaufman,Shani Shimon Paluch,Yael Laitman,Anne-Bine Skytte,Anne-Marie Gerdes,Inge Søkilde Pedersen,Sanne Traasdahl Moeller,Torben A Kruse,Uffe Birk Jensen,Joseph Vijai,Kara Sarrel,Mark E. Robson,Noah D. Kauff,Anna Marie Mulligan,Gord Glendon,Hilmi Ozcelik,Bent Ejlertsen,Finn Cilius Nielsen,Lars Jønson,Mette K. Andersen,Yuan Chun Ding,Linda Steele,Lenka Foretova,Alex Teulé,Conxi Lázaro,Joan Brunet,Miquel Angel Pujana,Phuong L. Mai,Jennifer T. Loud,Christine Walsh,Jenny Lester,Sandra Orsulic,Steven A. Narod,Josef Herzog,Sharon Sand,Silvia Tognazzo,Simona Agata,Tibor Vaszko,JoEllen Weaver,Alexandra V. Stavropoulou,Saundra S. Buys,Atocha Romero,Miguel de la Hoya,Kristiina Aittomäki,Taru A. Muranen,Mercedes Durán,Wendy K. Chung,Adriana Lasa,Cecilia M. Dorfling,Alexander Miron,Javier Benitez,Leigha Senter,Dezheng Huo,Salina B. Chan,Anna P. Sokolenko,Jocelyne Chiquette,Laima Tihomirova,Tara M. Friebel,Bjarni A. Agnarsson,Karen H. Lu,Flavio Lejbkowicz,Paul A. James,Per Hall,Alison M. Dunning,Daniel C. Tessier,Julie M. Cunningham,Susan L. Slager,Chen Wang,Steven N. Hart,Kristen N. Stevens,Jacques Simard,Tomi Pastinen,Vernon S. Pankratz,Kenneth Offit,Douglas F. Easton,Georgia Chenevix-Trench,Antonis C. Antoniou +261 more
TL;DR: It is estimated that the breast cancer lifetime risks for the5% of BRCA1 carriers at lowest risk are 28%–50% compared to 81%–100% for the 5% at highest risk, and the ovarian cancer lifetime risk is 63% or higher, based on the known cancer risk-modifying loci.
Journal ArticleDOI
Somatically mutated Ig VH3-21 genes characterize a new subset of chronic lymphocytic leukemia
Gerard Tobin,Ulf Thunberg,A. Johnson,Ingrid Thörn,Ola Söderberg,Magnus Hultdin,Johan Botling,Gunilla Enblad,Jan Sällström,Christer Sundström,Göran Roos,Richard Rosenquist +11 more
TL;DR: Interestingly, the subset of mutated cases using the V(H)3-21 gene displayed distinctive genotypic/phenotypic characteristics with shorter average length of the complementarity determining region 3 and clonal expression of lambda light chains, and showed significantly shorter survival than other mutated cases.
Downregulation of Death-Associated Protein Kinase 1 (DAPK1 )i n Chronic Lymphocytic Leukemia
Aparna Raval,Stephan M. Tanner,John C. Byrd,Elizabeth Angerman,James D. Perko,Shih-Shih Chen,Michael R. Grever,David M. Lucas,Jennifer J. Matkovic,Thomas S. Lin,Thomas J. Kipps,Fiona Murray,Dennis D. Weisenburger,Warren G. Sanger,Jane F. Lynch,Mary Jansen,Yuko Yoshinaga,Richard Rosenquist,Pieter J. de Jong,Penny Coggill,Stephan Beck,Henry T. Lynch,Albert de la Chapelle,Christoph Plass +23 more
TL;DR: It is shown that loss or reduced expression of death-associated protein kinase 1 (DAPK1) underlies cases of heritable predisposition to CLL and the majority of sporadic CLL.
Journal ArticleDOI
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia.
Aparna Raval,Stephan M. Tanner,John C. Byrd,Elizabeth Angerman,James D. Perko,Shih Shih Chen,Björn Hackanson,Björn Hackanson,Michael R. Grever,David M. Lucas,Jennifer J. Matkovic,Thomas S. Lin,Thomas J. Kipps,Fiona Murray,Dennis D. Weisenburger,Warren G. Sanger,Jane F. Lynch,Patrice Watson,Mary Jansen,Yuko Yoshinaga,Richard Rosenquist,Pieter J. de Jong,Penny Coggill,Stephan Beck,Henry T. Lynch,Albert de la Chapelle,Christoph Plass +26 more
TL;DR: In this article, the authors show that loss or reduced expression of death-associated protein kinase 1 (DAPK1) underlies cases of heritable predisposition to CLL and the majority of sporadic CLL cases.