S
Suzanne J. Brown
Researcher at University of Western Australia
Publications - 9
Citations - 759
Suzanne J. Brown is an academic researcher from University of Western Australia. The author has contributed to research in topics: Thyroid peroxidase & Thyroid disease. The author has an hindex of 8, co-authored 9 publications receiving 657 citations. Previous affiliations of Suzanne J. Brown include Diabetes Australia & Curtin University.
Papers
More filters
Journal ArticleDOI
Age-related changes in thyroid function: a longitudinal study of a community-based cohort.
Alexandra Bremner,Peter Feddema,Peter J. Leedman,Suzanne J. Brown,John Beilby,Ee Mun Lim,Ee Mun Lim,Scott Wilson,Peter O'Leary,John P. Walsh +9 more
TL;DR: Aging is associated with increased serum TSH concentrations, with no change in free T(4) concentrations, and the largest TSH increase is in people with the lowest TSH at baseline, which suggests that the T SH increase arises from age-related alteration in the TSH set point or reduced TSH bioactivity rather than occult thyroid disease.
Journal ArticleDOI
Thyrotropin and thyroid antibodies as predictors of hypothyroidism: A 13-year, longitudinal study of a community-based cohort using current immunoassay techniques
John P. Walsh,Alexandra Bremner,Peter Feddema,Peter J. Leedman,Peter J. Leedman,Suzanne J. Brown,Peter O'Leary,Peter O'Leary +7 more
TL;DR: The use of TSH cutoffs of 2.5 and 4.0 mU/liter, combined with thyroid antibodies, provides a clinically useful estimate of the long-term risk of hypothyroidism.
Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease
Marco Medici,Eleonora Porcu,Giorgio Pistis,Alexander Teumer,Suzanne J. Brown,Richard A. Jensen,Rajesh Rawal,Greet Roef,Theo S. Plantinga,Sita H. Vermeulen,Jari Lahti,Matthew J. Simmonds,Lise Lotte N. Husemoen,Rachel M. Freathy,Beverley M. Shields,Diana Pietzner,Rebecca Nagy,Linda Broer,Layal Chaker,Tim I M Korevaar,Maria Grazia Plia,Cinzia Sala,Uwe Voelker,J. Brent Richards,Fred C.G.J. Sweep,Christian Gieger,Tanguy Corre,Eero Kajantie,Betina H. Thuesen,Youri Taes,W. Edward Visser,Andrew T. Hattersley,Juergen Kratzsch,Alexander Hamilton,W. G. Li,Georg Homuth,Monia Lobina,Stefano Mariotti,Nicole Soranzo,Massimiliano Cocca,Matthias Nauck,Christin Spielhagen,Alec H. Ross,Alice M. Arnold,Martijn van de Bunt,Sandya Liyanarachchi,Margit Heier,Hans Joergen Grabe,Corrado Masciullo,Tessel E. Galesloot,Ee Mun Lim,Eva Reischl,Peter J. Leedman,Sandra Lai,Alessandro P Delitala,Alexandra Bremner,David I. W. Philips,John Beilby,Antonella Mulas,Matteo Vocale,Gonçalo R. Abecasis,Tom Forsén,Alan James,Elisabeth Widen,Jennie Hui,Holger Prokisch,Ernst E. Rietzschel,Aarno Palotie,Peter Feddema,Stephen J. Fletcher,Katharina Schramm,Jerome I. Rotter,Alexander Kluttig,Doerte Radke,Michela Traglia,Gabriela L. Surdulescu,Huiling He,Jayne A. Franklyn,Daniel Tiller,Bijay Vaidya,Tim De Meyer,Torben Jørgensen,Johan G. Eriksson,Peter O'Leary,Eric Wichmann,Ad R. M. M. Hermus,Bruce M. Psaty,Till Ittermann,Albert Hofman,Emanuele Bosi,David Schlessinger,Henri Wallaschofski,Nicola Pirastu,Yurii S. Aulchenko,Albert de la Chapelle,Romana T. Netea-Maier,Stephen C. L. Gough,Henriette E. Meyer zu Schwabedissen,Timothy M. Frayling,Jean-Marc Kaufman,Allan Linneberg,Katri Raeikkoenen,Johannes W. A. Smit,Lambertus A. Kiemeney,Fernando Rivadeneira,André G. Uitterlinden,John P. Walsh,Christa Meisinger,Martin den Heijer,Theo J. Visser,Tim D. Spector,Scott Wilson,Henry Voelzke,Anne R. Cappola,Daniela Toniolo,Serena Sanna,Silvia Naitza,Robin P. Peeters +117 more
TL;DR: The results provide insight into why individuals with thyroid autoimmunity do or do not eventually develop thyroid disease, and these markers may therefore predict which TPOAb-positives are particularly at risk of developing clinical thyroid dysfunction.
Journal ArticleDOI
The Importance of Measuring Ionized Calcium in Characterizing Calcium Status and Diagnosing Primary Hyperparathyroidism
Gregory S. Y. Ong,John P. Walsh,Bronwyn G. A. Stuckey,Suzanne J. Brown,Enrico Rossi,Jennifer L. Ng,Hieu Nguyen,G. Neil Kent,Ee Mun Lim +8 more
TL;DR: In abnormal calcium states, tCa frequently disagrees with iCa in classifying calcium status, and Measurement of iCa is required to accurately assess calcium status and improve diagnostic accuracy.
Journal ArticleDOI
Genetic Loci Linked to Pituitary-Thyroid Axis Set Points: A Genome-Wide Scan of a Large Twin Cohort
Vijay Panicker,Vijay Panicker,Scott Wilson,Scott Wilson,Tim D. Spector,Suzanne J. Brown,Bernet S. Kato,P.W. Reed,Mario Falchi,J. Brent Richards,Gabriela L. Surdulescu,Ee Mun Lim,Steven J. Fletcher,John P. Walsh +13 more
TL;DR: This study has identified eight genomic locations with linkage of LOD of 2.0 or greater that should enable targeted positional candidate and positional cloning studies to advance the understanding of genetic control of the pituitary-thyroid axis.