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Sven Hoffner

Researcher at Swedish Institute

Publications -  32
Citations -  2609

Sven Hoffner is an academic researcher from Swedish Institute. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 21, co-authored 32 publications receiving 2453 citations. Previous affiliations of Sven Hoffner include University of the Sciences.

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Emergence of New Forms of Totally Drug-Resistant Tuberculosis Bacilli: Super Extensively Drug-Resistant Tuberculosis or Totally Drug-Resistant Strains in Iran

TL;DR: In this article, the emergence of resistant bacilli (totally drug-resistant [TDR] or super extensively drug resistant [XDR] tuberculosis [TB] strains) among patients with multidrug-resistant TB (MDR-TB) was documented.
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Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

TL;DR: Molecular diagnostics that include markers for rifampicin resistance alone will be insufficient to identify pre-MDR strains, and incorporation of knowledge of polymorphisms that occur before the emergence of multidrug resistance, particularly katG p.Ser315Thr, into molecular diagnostics should enable targeted treatment of patients with pre-mDR-TB to prevent further development of MDR- TB.
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Spread of Drug-Resistant Pulmonary Tuberculosis in Estonia

TL;DR: Restriction fragment length polymorphism (RFLP) analysis of 209Mycobacterium tuberculosis clinical isolates obtained from newly detected pulmonary tuberculosis patients in Estonia during 1994 showed that 61 isolates belonged to a genetically closely related group of isolates, family A, with a predominant IS6110 banding pattern.
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Multidrug-resistant tuberculosis in Belarus: the size of the problem and associated risk factors

TL;DR: MDR-TB is very common among TB patients throughout Belarus and the numerous risk factors identified call not only for stronger collaboration between TB and HIV control programmes, but also for the implementation of innovative measures to accelerate the detection of TB resistance and improve treatment adherence.