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Sven Saussez

Researcher at University of Mons

Publications -  338
Citations -  10551

Sven Saussez is an academic researcher from University of Mons. The author has contributed to research in topics: Laryngopharyngeal reflux & Medicine. The author has an hindex of 38, co-authored 301 publications receiving 7310 citations. Previous affiliations of Sven Saussez include University of Mons-Hainaut & Free University of Brussels.

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Towards neuroimmunotherapy for cancer: the neurotransmitters glutamate, dopamine and GnRH-II augment substantially the ability of T cells of few head and neck cancer patients to perform spontaneous migration, chemotactic migration and migration towards the autologous tumor, and also elevate markedly the expression of CD3zeta and CD3epsilon TCR-associated chains.

TL;DR: A novel term is coined-‘Neuroimmunotherapy’ for this new form of T cell immunotherapy, based on the direct activation of the patient’s own T cells by Neurotransmitters, which could be reduced to practice by rather simple, painless and repeated/periodical removal of peripheral T cells from the cancer patients.
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Restoring p53 Function in Head and Neck Squamous Cell Carcinoma to Improve Treatments

TL;DR: Therapeutic strategies targeting p53 in HNSCC can be divided into three categories related to three subtypes encompassing WT p53, mutated p53 and HPV-positive H NSCC, with a new classification of such cancers based on p53 mutation status and HPV infection.
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The helicase-like transcription factor is a strong predictor of recurrence in hypopharyngeal but not in laryngeal squamous cell carcinomas

TL;DR: The aim is to characterize the HLTF protein variants expressed in biopsy specimens of head and neck squamous cell carcinoma as well as the HeLa cell line to examine the immunohistochemical expression of helicase‐like transcription factor in relation to the prognosis of hypopharyngeal and laryngeals squamouscell carcinomas.
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A comparison of survival lifetime of the Provox and the Provox2 voice prosthesis.

TL;DR: The survival lifetime of the second generation Provox®2 valve is shorter than the lifetime of this voice prosthesis, which could be due to the difference in elasticity of these valves that could lead to a different level of colonization and invasion of the valves by micro-organisms.