S
Svenja Schneegans
Researcher at University of Hamburg
Publications - 6
Citations - 99
Svenja Schneegans is an academic researcher from University of Hamburg. The author has contributed to research in topics: Circulating tumor cell & Cancer. The author has an hindex of 3, co-authored 4 publications receiving 32 citations.
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Journal ArticleDOI
ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium.
Justine Münsterberg,Desiree Loreth,Laura Brylka,Stefan Werner,Jana Karbanová,Monja Gandrass,Svenja Schneegans,Katharina Besler,Fabienne Hamester,Jose Ramon Robador,Alexander Bauer,Stefan W. Schneider,Michaela Wrage,Katrin Lamszus,Jakob Matschke,Yogesh K. Vashist,Güntac Uzunoglu,Stefan Steurer,Andrea Kristina Horst,Leticia Oliveira-Ferrer,Markus Glatzel,Thorsten Schinke,Denis Corbeil,Klaus Pantel,Cecile L. Maire,Harriet Wikman +25 more
TL;DR: The findings suggest that elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells, and A LCAM could be targeted to reduce the occurrence of BM.
Journal ArticleDOI
Pre-Analytical and Analytical Variables of Label-Independent Enrichment and Automated Detection of Circulating Tumor Cells in Cancer Patients.
Claudia Koch,Simon A. Joosse,Svenja Schneegans,Okka J. W. Wilken,Melanie Janning,Desiree Loreth,Volkmar Müller,Katharina Prieske,Malgorzata Banys-Paluchowski,Ludwig J Horst,Sonja Loges,Sven Peine,Harriet Wikman,Tobias M. Gorges,Klaus Pantel +14 more
TL;DR: Within the EU/IMI CANCER-ID consortium, the Parsortix system (ANGLE plc) which enables label-independent CTC enrichment from whole blood based on increased size and deformability of these tumor cells compared to leukocytes is tested.
Journal ArticleDOI
CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
Desiree Loreth,Moritz Schuette,Jenny Zinke,Malte Mohme,Andras Piffko,Svenja Schneegans,Julia T. Stadler,Melanie Janning,Melanie Janning,Melanie Janning,Sonja Loges,Sonja Loges,Sonja Loges,Simon A. Joosse,Katrin Lamszus,Manfred Westphal,Volkmar Müller,Markus Glatzel,Jakob Matschke,Christoffer Gebhardt,Stefan W. Schneider,Iwona Belczacka,Beate Volkmer,Rüdiger Greinert,Marie-Laure Yaspo,Patrick N. Harter,Klaus Pantel,Harriet Wikman +27 more
TL;DR: It is shown that a size-based microfluidic approach in combination with a semi-automated cell recognition system are well suited for CTC detection in BM patients and allow further characterization of tumor cells potentially derived from BM.
Journal ArticleDOI
Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients.
Svenja Schneegans,Lelia Lück,Katharina Besler,Leonie Bluhm,Julia-Christina Stadler,Janina Staub,Rüdiger Greinert,Beate Volkmer,Mikael Kubista,Christoffer Gebhardt,Alexander Sartori,Darryl Irwin,Elina Serkkola,Taija af Hällström,Evi Lianidou,Markus Sprenger-Haussels,Melanie A. Hussong,Peter Mohr,Stefan W. Schneider,Jonathan M Shaffer,Klaus Pantel,Harriet Wikman +21 more
TL;DR: In summary, high‐quality CTCs, ctDNA, and miRNA data from a single blood tube can be obtained, however, the choice of blood collection tubes is a critical pre‐analytical variable.
Journal ArticleDOI
Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance.
TL;DR: In this article , the potential clinical relevance of these interactions as biomarkers or as targets for anti-metastatic therapies was discussed, as well as potential clinical significance of the interactions between CTCs and different hematopoietic cells.