S
Sylvia Kamphuis
Researcher at Boston Children's Hospital
Publications - 81
Citations - 2983
Sylvia Kamphuis is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Arthritis & Internal medicine. The author has an hindex of 28, co-authored 71 publications receiving 2202 citations. Previous affiliations of Sylvia Kamphuis include Erasmus University Medical Center & Erasmus University Rotterdam.
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Journal ArticleDOI
Systemic Lupus Erythematosus in Children and Adolescents
Deborah M. Levy,Sylvia Kamphuis +1 more
TL;DR: The epidemiology, common clinical features, and complications of the disease are reviewed, and the available treatment options are discussed.
Journal ArticleDOI
EULAR/PReS standards and recommendations for the transitional care of young people with juvenile-onset rheumatic diseases
Helen E. Foster,Kirsten Minden,Daniel Clemente,Leticia Leon,Leticia Leon,Janet E. McDonagh,Sylvia Kamphuis,Karin Berggren,Philomine A van Pelt,Carine Wouters,Jennifer M Waite-Jones,Rachel Tattersall,Ruth Wyllie,Simon Stones,Alberto Martini,Tamás Constantin,Susanne Schalm,Berna Eren Fidanci,Burak Erer,Erkan Dermikaya,Seza Ozen,Loreto Carmona +21 more
TL;DR: 12 specific recommendations for YP with jRMD focused on transitional care included: high-quality, multidisciplinary care starting in early adolescence; the integral role of a transition co-ordinator; transition policies and protocols; efficient communications; transfer documentation.
Journal ArticleDOI
European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis-the SHARE initiative.
Seza Ozen,Stephen D. Marks,Paul A. Brogan,Noortje Groot,Noortje Groot,Nienke de Graeff,Tadej Avcin,Brigitte Bader-Meunier,Pavla Dolezalova,Brian M. Feldman,Isabelle Koné-Paut,Pekka Lahdenne,Liza J McCann,Clarissa Pilkington,Angelo Ravelli,Annet van Royen,Yosef Uziel,Bas Vastert,Nico M Wulffraat,Sylvia Kamphuis,Michael W. Beresford +20 more
TL;DR: The SHARE initiative provides international, evidence-based recommendations for the diagnosis and treatment of IgAV that will facilitate improvement and uniformity of care.
Journal ArticleDOI
Time to treatment as an important factor for the response to methotrexate in juvenile idiopathic arthritis
HM Albers,Judith A.M. Wessels,R.J.H.M. van der Straaten,D. M. C. Brinkman,L. W. A. Suijlekom-Smit,Sylvia Kamphuis,HJ Girschick,Carine Wouters,Marco W. Schilham,S. le Cessie,Twj Huizinga,R. ten Cate,R. ten Cate,Henk-Jan Guchelaar +13 more
TL;DR: In children with JIA, the time from diagnosis to start of MTX appears to be an important factor for MTX response, and the results suggest that an earlier start ofMTX treatment will lead to an increased response.
Journal ArticleDOI
The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat-shock protein 60 capable of producing the regulatory cytokine interleukin-10.
I. M. de Kleer,Sylvia Kamphuis,Ger T. Rijkers,L. Scholtens,G. Gordon,W. de Jager,R. Häfner,R. van de Zee,W. van Eden,Wietse Kuis,Berent J. Prakken +10 more
TL;DR: The results show that T cells responding to human Hsp60 in oligoarticular JIA patients express CD30, and during active phases of the disease, these T cells have a cytokine profile with a high IL-10:IFNgamma ratio.