T
T. Derek V. Cooke
Researcher at Queen's University
Publications - 22
Citations - 1455
T. Derek V. Cooke is an academic researcher from Queen's University. The author has contributed to research in topics: Valgus & Osteoarthritis. The author has an hindex of 14, co-authored 22 publications receiving 1271 citations.
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Journal ArticleDOI
Varus and valgus alignment and incident and progressive knee osteoarthritis
Leena Sharma,Jing Song,Dorothy D. Dunlop,David T. Felson,Cora E. Lewis,Neil A. Segal,James C. Torner,T. Derek V. Cooke,Jean Hietpas,John A. Lynch,Michael C. Nevitt +10 more
TL;DR: In knees with osteoarthritis, varus and valgus alignment each increased the risk of progression in the biomechanically stressed compartment, and Varus but not valGus alignment increased therisk of incident tibiofemoral osteOarthritis.
Journal Article
Frontal plane knee alignment: a call for standardized measurement.
TL;DR: A system of measurements based on geometric analysis of the femur, tibia, and knee joint surfaces is discussed, and a standardized methodology for measurement and computation of these parameters is discussed.
Journal ArticleDOI
Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: Findings from the multicenter osteoarthritis study and the osteoarthritis initiative
David T. Felson,David T. Felson,Jingbo Niu,K. Douglas Gross,K. Douglas Gross,Martin Englund,Martin Englund,Leena Sharma,T. Derek V. Cooke,Ali Guermazi,Frank W. Roemer,Neil A. Segal,Joyce Goggins,C. Elizabeth Lewis,Charles B. Eaton,Michael C. Nevitt +15 more
TL;DR: A strong relationship of valgus malalignment with progressive lateral meniscal damage is found, which may cause these effects, in part, by increasing the risk of meniscalDamage.
Journal ArticleDOI
The role of varus and valgus alignment in the initial development of knee cartilage damage by MRI: the MOST study
Leena Sharma,Joan S. Chmiel,Orit Almagor,David T. Felson,Ali Guermazi,Frank W. Roemer,Frank W. Roemer,Cora E. Lewis,Neil A. Segal,James C. Torner,T. Derek V. Cooke,Jean Hietpas,John A. Lynch,Michael C. Nevitt +13 more
TL;DR: It is found that varus increases the risk of the initial development of knee osteoarthritis and valgus was associated with a reduced risk of incident lateral and medial damage, respectively.
Journal ArticleDOI
Analysis of limb alignment in the pathogenesis of osteoarthritis: a comparison of Saudi Arabian and Canadian cases
TL;DR: An association between femoral deformity (CH) and OA, first reported in Canadians with OA (COA), was confirmed in SOA (especially in males of all ages); the condition implies heightened mechanical risk of onset or progression at medial joint surfaces.