T
Takehiro Kamo
Researcher at University of Tokyo
Publications - 9
Citations - 451
Takehiro Kamo is an academic researcher from University of Tokyo. The author has contributed to research in topics: Angiotensin II receptor type 1 & Internal medicine. The author has an hindex of 7, co-authored 7 publications receiving 316 citations.
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Journal ArticleDOI
Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure
Takehiro Kamo,Hiroshi Akazawa,Wataru Suda,Wataru Suda,Akiko Saga-Kamo,Yu Shimizu,Hiroki Yagi,Qing Liu,Seitaro Nomura,Atsuhiko T. Naito,Norifumi Takeda,Mutsuo Harada,Haruhiro Toko,Hidetoshi Kumagai,Yuichi Ikeda,Eiki Takimoto,Jun-ichi Suzuki,Kenya Honda,Hidetoshi Morita,Masahira Hattori,Masahira Hattori,Issei Komuro +21 more
TL;DR: It is suggested that patients with HF harbor significantly altered gut microbiota, which varies further according to age, and new concept of heart-gut axis has a great potential for breakthroughs in the development of novel diagnostic and therapeutic approach for HF.
Journal ArticleDOI
Cardiac Nonmyocytes in the Hub of Cardiac Hypertrophy
TL;DR: In this review, recent progress in the understanding of the importance of nonmyocytes as a hub for induction of cardiac hypertrophy is summarized with an emphasis of the contribution of noncontact communication mediated by diffusible factors between cardiomyocytes and nonmyocyte in the heart.
Journal ArticleDOI
Novel Concept of a Heart-Gut Axis in the Pathophysiology of Heart Failure.
TL;DR: The novel concept of a heart-gut axis may lead to breakthroughs in the development of innovative diagnostics and therapeutic approaches for HF.
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Pleiotropic Effects of Angiotensin II Receptor Signaling in Cardiovascular Homeostasis and Aging
TL;DR: Physiological or genetic blockade of AT1 receptor signaling in rodents has been shown to prevent the progression of aging-related phenotypes and promote longevity, and pleiotropic effects in cardiovascular homeostasis and aging are reviewed.
Journal ArticleDOI
Angiotensin II receptor blockade promotes repair of skeletal muscle through down-regulation of aging-promoting C1q expression
Chizuru Yabumoto,Hiroshi Akazawa,Rie Yamamoto,Masamichi Yano,Yoko Kudo-Sakamoto,Tomokazu Sumida,Tomokazu Sumida,Takehiro Kamo,Hiroki Yagi,Yu Shimizu,Akiko Saga-Kamo,Atsuhiko T. Naito,Atsuhiko T. Naito,Atsuhiko T. Naito,Toru Oka,Toru Oka,Jong-Kook Lee,Jun-ichi Suzuki,Yasushi Sakata,Etsuko Uejima,Issei Komuro,Issei Komuro +21 more
TL;DR: The results suggest that AT1 receptor blockade improves muscle repair and regeneration through down-regulation of the aging-promoting C1q-Wnt/β-catenin signaling pathway.