Takeo Kato

TL;DR: The successful establishment of ES-like cells from neonatal mouse testis were phenotypically similar to ES/EG cells except in their genomic imprinting pattern and differentiated into various types of somatic cells in vitro under conditions used to induce the differentiation of ES cells.

TL;DR: Under appropriate induction conditions, the sphere-derived cells acquired the phenotypic properties in vitro of neurons, skeletal myoblasts, and beating cardiomyocytes, as well as adipocytes, osteoblast, and chondrocytes.

TL;DR: A novel stepwise culture method for the selective expansion of mesenchymal cells from cell aggregations called embryoid bodies is developed, which facilitates further utilization of ES and iPS cells in both developmental and pathological muscle research and in serving as a practical donor source for cell therapy of muscle diseases.

TL;DR: The usefulness of syndecan‐ 1, Notch‐1, and integrin‐β1 as NSC markers are indicated and there was no distinct difference in neurosphere formation efficiency between Hoechst 33342‐stained side population cells and main population cells, although the former are known to have a stem cell phenotype in various tissues.

TL;DR: The clinical relevance of assessment of muscle thickness across a broad spectrum of individuals with CP was established and the degree of knee flexion contracture correlated positively with the MAS rating of the knee flexor muscles and negatively with the MTQ.