T
Tao Feng
Researcher at Case Western Reserve University
Publications - 24
Citations - 962
Tao Feng is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Genome-wide association study & Genetic association. The author has an hindex of 14, co-authored 24 publications receiving 861 citations. Previous affiliations of Tao Feng include Heilongjiang University & Michigan Technological University.
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Journal ArticleDOI
Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension
Xiaofeng Zhu,Tao Feng,Tao Feng,Bamidele O. Tayo,Jingjing Liang,J. Hunter Young,Nora Franceschini,Jennifer A. Smith,Lisa R. Yanek,Yan V. Sun,Todd L. Edwards,Wei Chen,Mike A. Nalls,Ervin R. Fox,Michèle M. Sale,Erwin P. Bottinger,Charles N. Rotimi,Yongmei Liu,Barbara McKnight,Kiang Liu,Donna K. Arnett,Aravinda Chakravati,Richard S. Cooper,Susan Redline +23 more
TL;DR: This study strongly suggests that analyzing multiple phenotypes can improve statistical power and that such analysis can be executed with the summary statistics from GWASs, and provides a way to study a cross phenotype (CP) association by using summary Statistics fromGWASs of multiple phenotype.
Journal ArticleDOI
Detecting rare variants for complex traits using family and unrelated data.
TL;DR: This work proposes two designs, sibpair and unrelated‐case designs, to detect rare genetic variants in either a candidate gene‐based or genome‐wide association analysis, and shows that they can detect and classify together rare risk haplotypes using a relatively small sample with either of these designs, and can also be applied to resequencing data.
Journal ArticleDOI
Two-marker association tests yield new disease associations for coronary artery disease and hypertension
TL;DR: It is shown that novel, multiple-marker, statistical methods can be of use in finding variants in GWAS and many new, associated variants for both CAD and HTN are described.
Journal ArticleDOI
Genome-wide association of anthropometric traits in African- and African-derived populations
Sun J. Kang,Charleston W. K. Chiang,Charleston W. K. Chiang,Charleston W. K. Chiang,Cameron D. Palmer,Cameron D. Palmer,Bamidele O. Tayo,Guillaume Lettre,Guillaume Lettre,Johannah L. Butler,Johannah L. Butler,Rachel Hackett,Adebowale Adeyemo,Candace Guiducci,Ilze Berzins,Thutrang T. Nguyen,Thutrang T. Nguyen,Tao Feng,Amy Luke,Daniel Shriner,Kristin G. Ardlie,Charles N. Rotimi,Rainford J. Wilks,Terrence Forrester,Colin A. McKenzie,Helen N. Lyon,Helen N. Lyon,Richard S. Cooper,Xiaofeng Zhu,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn +31 more
TL;DR: The results suggest that there are not multiple loci with strong effects on anthropometric traits in African-derived populations and that sample sizes comparable to those needed in European GWA studies will be required to identify replicable associations.
Journal ArticleDOI
Genome-wide searching of rare genetic variants in WTCCC data
Tao Feng,Xiaofeng Zhu +1 more
TL;DR: The analysis suggests that searching for rare genetic variants is feasible in current GWA studies and candidate gene studies, and the results can severe as guides to future resequencing studies to identify the underlying rare functional variants.