T
Tao Guo
Researcher at Chinese Academy of Sciences
Publications - 65
Citations - 1402
Tao Guo is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 16, co-authored 47 publications receiving 852 citations.
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Journal ArticleDOI
Composite CD-MOF nanocrystals-containing microspheres for sustained drug delivery
Haiyan Li,Haiyan Li,Nana Lv,Nana Lv,Xue Li,Xue Li,Botao Liu,Botao Liu,Jing Feng,Xiaohong Ren,Tao Guo,Dawei Chen,J. Fraser Stoddart,Ruxandra Gref,Jiwen Zhang,Jiwen Zhang +15 more
TL;DR: These composite microspheres, composed of CD-MOF nanocrystals embedded in a biocompatible polymer (PAA) matrix, constitute an efficient and pharmaceutically acceptable MOF-based carrier for sustained drug release.
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Ultrafine Silver Nanoparticles Embedded in Cyclodextrin Metal-Organic Frameworks with GRGDS Functionalization to Promote Antibacterial and Wound Healing Application.
Shailendra Shakya,Yaping He,Xiaohong Ren,Tao Guo,Abi Maharjan,Ting Luo,Ting Luo,Tingting Wang,Tingting Wang,Ramesh Dhakhwa,Balmukunda Regmi,Haiyan Li,Ruxandra Gref,Jiwen Zhang +13 more
TL;DR: A template-guided synthesis of ultrafine Ag NPs of around 2 nm using water-soluble and biocompatible γ-cyclodextrin metal-organic frameworks (CD-MOFs) is reported, achieving dual functions of reduced particle size and enhanced stability.
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Microwave-Assisted Rapid Synthesis of γ-Cyclodextrin Metal–Organic Frameworks for Size Control and Efficient Drug Loading
Botao Liu,Botao Liu,Yaping He,Liping Han,Vikramjeet Singh,Xiaonan Xu,Tao Guo,Fanyue Meng,Xu Xu,Peter York,Zhaoxin Liu,Jiwen Zhang,Jiwen Zhang +12 more
TL;DR: The micron and nanometer-sized γ-cyclodextrin metal-organic frameworks (γ-CD-MOFs) were successfully synthesized using the microwave technique for the first time for rapid and facile synthesis as discussed by the authors.
Journal ArticleDOI
Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding
TL;DR: A facile and one step-method was developed to enhance the water stability of CD-MOF nanoparticles through surface modification with cholesterol, which resulted in well tolerated in vivo and could increase up to 4 times the blood half-life of DOX.
Journal ArticleDOI
Drug nanoclusters formed in confined nano-cages of CD-MOF: dramatic enhancement of solubility and bioavailability of azilsartan
Yuanzhi He,Yuanzhi He,Wei Zhang,Wei Zhang,Tao Guo,Guoqing Zhang,Wei Qin,Wei Qin,Liu Zhang,Caifen Wang,Weifeng Zhu,Ming Yang,Xiaoxiao Hu,Vikramjeet Singh,Li Wu,Li Wu,Ruxandra Gref,Jiwen Zhang +17 more
TL;DR: This research demonstrates a dual molecular mechanism of complexation and nanoclusterization in CD-MOF leading to significant improvement in the bioavailability of insoluble drugs.