T
Tara L. Moore
Researcher at Boston University
Publications - 64
Citations - 2081
Tara L. Moore is an academic researcher from Boston University. The author has contributed to research in topics: Prefrontal cortex & Medicine. The author has an hindex of 21, co-authored 56 publications receiving 1692 citations. Previous affiliations of Tara L. Moore include University of Pittsburgh.
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Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain--a primate study.
Kullervo Hynynen,Nathan McDannold,Greg T. Clement,Ferenc A. Jolesz,Eyal Zadicario,Ronald J. Killiany,Tara L. Moore,Douglas Rosen +7 more
TL;DR: MRI-guided and monitored focused ultrasound thermal surgery of brain through intact skull was tested in rhesus monkeys and showed that by applying surface cooling the skin and skull surface can be protected, and that the brain surface temperature becomes the limiting factor.
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Development of a Computerized Adaptive Test for Depression
Robert D. Gibbons,David J. Weiss,Paul A. Pilkonis,Ellen Frank,Tara L. Moore,Jong Bae Kim,David J. Kupfer +6 more
TL;DR: The development of a computerized adaptive test for depression, called the Computerized Adaptive Test-Depression Inventory (CAT-DI), that decreases patient and clinician burden and increases measurement precision is developed.
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Normal aging results in decreased synaptic excitation and increased synaptic inhibition of layer 2/3 pyramidal cells in the monkey prefrontal cortex.
TL;DR: Assessment of excitatory and inhibitory postsynaptic currents in layer 2/3 pyramidal cells in in vitro slices of the PFC from behaviorally characterized young and aged rhesus monkeys found that aged monkeys were significantly impaired in performance on memory and executive system function tasks.
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Impairment in abstraction and set shifting in aged rhesus monkeys.
Tara L. Moore,Ronald J. Killiany,James G. Herndon,Douglas L. Rosene,Douglas L. Rosene,Mark B. Moss,Mark B. Moss +6 more
TL;DR: Assessment of executive function in a non-human primate model of normal human aging using the Conceptual Set Shifting Task (CSST) suggests an age-related decline in prefrontal cortex (PFC) functioning.
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Frontal connections and cognitive changes in normal aging rhesus monkeys: a DTI study.
Nikos Makris,Nikos Makris,George Papadimitriou,Andre van der Kouwe,David N. Kennedy,Steven M. Hodge,Anders M. Dale,Thomas Benner,Lawrence L. Wald,Ona Wu,David S. Tuch,Verne S. Caviness,Tara L. Moore,Ronald J. Killiany,Mark B. Moss,Mark B. Moss,Douglas L. Rosene,Douglas L. Rosene +17 more
TL;DR: The hypothesis that alterations to the integrity of these long association pathways connecting the frontal lobe with other forebrain regions contribute to cognitive impairments in normal aging is supported, and this is the first investigation reporting such alterations in the aging monkey.