Ted Tang Lee

TL;DR: It is demonstrated that non-invasive, transdermal time-regulated activation of cell-adhesive RGD peptide on implanted biomaterials regulates in vivo cell adhesion, inflammation, fibrous encapsulation, and vascularization of the material.

TL;DR: It is demonstrated that vinculin is not required for transmission of adhesive and traction forces but is necessary for myosin contractility-dependent adhesion strength and traction force and for the coupling of cell area and tractionforce.

TL;DR: By coating titanium plugs with precisely configured bits of a common extracellular matrix protein, fibronectin, Petrie et al. have deceived surrounding cells into accepting their disguised device, thereby enhancing tissue healing and integration of the titanium implant into bone.

TL;DR: It is found that simple FN adsorption onto poly(ethyl acrylate) surfaces, but not control polymers, triggered FN organization into a fibrillar network via interactions in the amino-terminal 70 kDa fragment, which is involved in the formation of cell-mediated FN fibrils.

TL;DR: The use of light to trigger cell adhesion to synthetic materials by controlling the presentation of the bioadhesive arginine-glycine-aspartic acid (RGD) oligopeptide with photoresponsive molecules is used.