Z
Zhao Lai
Researcher at Greehey Children's Cancer Research Institute
Publications - 93
Citations - 5168
Zhao Lai is an academic researcher from Greehey Children's Cancer Research Institute. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 31, co-authored 67 publications receiving 4343 citations. Previous affiliations of Zhao Lai include Chinese Academy of Sciences & University of Texas Health Science Center at San Antonio.
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Journal ArticleDOI
Major Ecological Transitions in Wild Sunflowers Facilitated by Hybridization
Loren H. Rieseberg,Olivier Raymond,David M. Rosenthal,Zhao Lai,Kevin Livingstone,Takuya Nakazato,Jennifer L. Durphy,Andrea E. Schwarzbach,Lisa A. Donovan,Christian Lexer +9 more
TL;DR: The same combinations of parental chromosomal segments required to generate extreme phenotypes in synthetic hybrids also occurred in ancient hybrids, and this possibility was tested through phenotypic and genomic comparisons of ancient and synthetic hybrids.
Journal ArticleDOI
The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution
Hélène Badouin,Jérôme Gouzy,Christopher J. Grassa,Christopher J. Grassa,Florent Murat,S. Evan Staton,Ludovic Cottret,Christine Lelandais-Brière,Gregory L. Owens,Sébastien Carrère,Baptiste Mayjonade,Ludovic Legrand,Navdeep Gill,Nolan C. Kane,Nolan C. Kane,John E. Bowers,Sariel Hübner,Sariel Hübner,Arnaud Bellec,Aurélie Bérard,Hélène Bergès,Nicolas Blanchet,Marie Claude Boniface,Dominique Brunel,Olivier Catrice,Nadia Chaidir,Nadia Chaidir,Clotilde Claudel,Cécile Donnadieu,Thomas Faraut,Ghislain Fievet,Nicolas Helmstetter,Matthew G. King,Matthew G. King,Steven J. Knapp,Zhao Lai,Marie-Christine Le Paslier,Yannick Lippi,Lolita Lorenzon,Jennifer R. Mandel,Gwenola Marage,Gwenaëlle Marchand,Elodie Marquand,Emmanuelle Bret-Mestries,Evan Morien,Savithri U. Nambeesan,Thuy Tien Nguyen,Thuy Tien Nguyen,Prune Pegot-Espagnet,Nicolas Pouilly,Frances Raftis,Erika Sallet,Thomas Schiex,Justine Thomas,Céline Vandecasteele,D. Varès,Felicity Vear,Sonia Vautrin,Martin Crespi,Brigitte Mangin,John M. Burke,Jérôme Salse,Stéphane Muños,Patrick Vincourt,Loren H. Rieseberg,Loren H. Rieseberg,Nicolas B. Langlade +66 more
TL;DR: It is found that the genomic architecture of flowering time has been shaped by the most recent whole-genome duplication, which suggests that ancient paralogues can remain in the same regulatory networks for dozens of millions of years.
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An F-box gene linked to the self-incompatibility (S) locus of Antirrhinum is expressed specifically in pollen and tapetum.
TL;DR: A novel F-box gene, AhSLF-S2, encoded by the S2 allele, with the expected features of the Sp gene was identified and defined a large gene family, named SLF (S locus F- box) family, which is highly polymorphic and is specifically expressed in tapetum, microspores and pollen grains in an allele-specific manner.
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Genomic islands of divergence are not affected by geography of speciation in sunflowers
Sébastien Renaut,Christopher J. Grassa,Sam Yeaman,Brook T. Moyers,Zhao Lai,Nolan C. Kane,Nolan C. Kane,John E. Bowers,John M. Burke,Loren H. Rieseberg,Loren H. Rieseberg +10 more
TL;DR: It is found that genetic divergence is lower in sympatric and parapatric comparisons, consistent with a role for gene flow in eroding neutral differences, and the results indicate that the functional architecture of genomes plays a larger role in shaping genomic divergence than does the geography of speciation.
Journal ArticleDOI
Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression
Subbarayalu Panneerdoss,Vijay Kumar Eedunuri,Pooja Yadav,Santosh Timilsina,Subapriya Rajamanickam,Suryavathi Viswanadhapalli,Nourhan Abdelfattah,Benjamin C. Onyeagucha,Xiadong Cui,Zhao Lai,Tabrez A. Mohammad,Yogesh K. Gupta,Tim H M Huang,Yufei Huang,Yi Chen,Manjeet K. Rao +15 more
TL;DR: A previously undefined role for m6A in cancer is unveiled and it is shown that the collaboration among writers-erasers-readers sets up the m 6A threshold to ensure the stability of progrowth/proliferation-specific genes, and protumorigenic stimulus, such as hypoxia.