T
Terese C. Hammond
Researcher at Missouri University of Science and Technology
Publications - 9
Citations - 373
Terese C. Hammond is an academic researcher from Missouri University of Science and Technology. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 4 publications receiving 350 citations.
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Journal ArticleDOI
In vivo indices of oxidative stress in lead-exposed C57BL/6 mice are reduced by treatment with meso-2,3-Dimercaptosuccinic Acid or N-acetylcysteine
Nuran Ercal,Piyanee Treeratphan,Terese C. Hammond,Richard H. Matthews,Neil H. Grannemann,Douglas R. Spitz +5 more
TL;DR: Results suggest that lead-induced oxidative stress in vivo can be mitigated by pharmacologic interventions, which encompass both chelating as well as thiol-mediated antioxidant functions.
Journal ArticleDOI
A role for oxidative stress in suppressing serum immunoglobulin levels in lead-exposed Fisher 344 rats.
Nuran Ercal,Rachel Neal,Piyanee Treeratphan,Paula Lutz,Terese C. Hammond,Phyllis A. Dennery,Douglas R. Spitz +6 more
TL;DR: It is suggested that oxidative stress contributes to suppressed serum Ig levels during lead intoxication in vivo, and that intervention with either a thiol antioxidant (NAC) or a metal chelator (DMSA) will alleviate this lead-induced suppression by correcting the prooxidant/antioxidant imbalance caused by lead exposure.
Journal ArticleDOI
N-acetylcysteine protects Chinese hamster ovary (CHO) cells from lead-induced oxidative stress
TL;DR: The results suggest that NAC can confer protection against lead-induced oxidative stress to CHO cells, possibly through the enhancement of the cell’s own antioxidant defense mechanisms.
Journal ArticleDOI
High-performance liquid chromatography assay for N-acetylcysteine in biological samples following derivatization with N-(1-pyrenyl)maleimide
TL;DR: A sensitive, rapid method for determining reduced N-acetylcysteine (NAC) concentration in biological samples has been developed which uses a modified reversed-phase high-performance liquid chromatography technique in conjunction with the derivatizing agent N-(1-pyrenyl)maleimide (NPM).
ReportDOI
Clinical Course of Two Patients with COVID-19 Respiratory Failure After Administration of the Anticancer Small Molecule, RRx-001
Terese C. Hammond,Raymond C. Lee,Bryan Oronsky,Tony R. Reid,Scott Caroen,Tiffany Juarez,Jaya Gill,Annie Heng,Santosh Kesari +8 more
TL;DR: In this article , two critically ill COVID-19 infected patients, who had exhausted all available treatment options, were treated with the small-molecule RRx-001 with subsequent improvement.