T
Teru Okitsu
Researcher at University of Tokyo
Publications - 120
Citations - 4148
Teru Okitsu is an academic researcher from University of Tokyo. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 30, co-authored 118 publications receiving 3728 citations. Previous affiliations of Teru Okitsu include Kyoto University & Okayama University.
Papers
More filters
Journal ArticleDOI
Metre-long cell-laden microfibres exhibit tissue morphologies and functions
Hiroaki Onoe,Teru Okitsu,Akane Itou,Midori Kato-Negishi,Riho Gojo,Daisuke Kiriya,Koji Sato,Shigenori Miura,Shintaroh Iwanaga,Kaori Kuribayashi-Shigetomi,Yukiko T. Matsunaga,Yuto Shimoyama,Shoji Takeuchi +12 more
TL;DR: Fibres encapsulating primary pancreatic islet cells and transplanted through a microcatheter into the subrenal capsular space of diabetic mice normalized blood glucose concentrations for about two weeks and may find use as templates for the reconstruction of fibre-shaped functional tissues that mimic muscle fibres, blood vessels or nerve networks in vivo.
Journal ArticleDOI
A new cell-permeable peptide allows successful allogeneic islet transplantation in mice
Hirofumi Noguchi,Masayuki Matsushita,Teru Okitsu,Teru Okitsu,Akiyoshi Moriwaki,Kazuhito Tomizawa,Sunghyun Kang,Sheng-Tian Li,Naoya Kobayashi,Shinichi Matsumoto,Koich Tanaka,Noriaki Tanaka,Hideki Matsui +12 more
TL;DR: A cell-permeable inhibitor of NFAT (nuclear factor of activated T cells) using the polyarginine peptide delivery system provided immunosuppression for fully mismatched islet allografts in mice and did not affect insulin secretion, whereas FK506 caused a dose-dependent decrease in insulin secretion.
Journal ArticleDOI
Injectable hydrogel microbeads for fluorescence-based in vivo continuous glucose monitoring
Hideaki Shibata,Yun Jung Heo,Teru Okitsu,Yukiko T. Matsunaga,Tetsuro Kawanishi,Shoji Takeuchi +5 more
TL;DR: It is found that the fluorescent beads provide sufficient intensity to transdermally monitor glucose concentrations in vivo, indicating the method has potential uses in highly-sensitive and minimally invasive continuous blood glucose monitoring.
Journal ArticleDOI
Long-term in vivo glucose monitoring using fluorescent hydrogel fibers.
TL;DR: It was found that the polyethylene glycol (PEG)-bonded polyacrylamide (PAM) hydrogel fibers reduced inflammation compared with PAM hydrogels fibers, transdermally glowed, and continuously responded to blood glucose concentration changes for up to 140 days, showing their potential application for long-term in vivo continuous glucose monitoring.
Journal ArticleDOI
Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes
Alejandro Soto-Gutierrez,Naoya Kobayashi,Jorge David Rivas-Carrillo,Nalu Navarro-Alvarez,Debaio Zhao,Teru Okitsu,Hirofumi Noguchi,Hesham Basma,Yashuhiko Tabata,Yong Chen,Kimiaki Tanaka,Michiki Narushima,Atsushi Miki,Tadayoshi Ueda,Hee-Sook Jun,Hee-Sook Jun,Ji-Won Yoon,Jane S. Lebkowski,Noriaki Tanaka,Ira J. Fox +19 more
TL;DR: Mouse embryonic stem cells are differentiated into hepatocytes by coculture with a combination of human liver nonparenchymal cell lines and fibroblast growth factor-2, human activin-A and hepatocyte growth factor to generate an alternative source of cells for BAL support.