Teru Okitsu

TL;DR: Fibres encapsulating primary pancreatic islet cells and transplanted through a microcatheter into the subrenal capsular space of diabetic mice normalized blood glucose concentrations for about two weeks and may find use as templates for the reconstruction of fibre-shaped functional tissues that mimic muscle fibres, blood vessels or nerve networks in vivo.

TL;DR: A cell-permeable inhibitor of NFAT (nuclear factor of activated T cells) using the polyarginine peptide delivery system provided immunosuppression for fully mismatched islet allografts in mice and did not affect insulin secretion, whereas FK506 caused a dose-dependent decrease in insulin secretion.

TL;DR: It is found that the fluorescent beads provide sufficient intensity to transdermally monitor glucose concentrations in vivo, indicating the method has potential uses in highly-sensitive and minimally invasive continuous blood glucose monitoring.

TL;DR: It was found that the polyethylene glycol (PEG)-bonded polyacrylamide (PAM) hydrogel fibers reduced inflammation compared with PAM hydrogels fibers, transdermally glowed, and continuously responded to blood glucose concentration changes for up to 140 days, showing their potential application for long-term in vivo continuous glucose monitoring.

TL;DR: Mouse embryonic stem cells are differentiated into hepatocytes by coculture with a combination of human liver nonparenchymal cell lines and fibroblast growth factor-2, human activin-A and hepatocyte growth factor to generate an alternative source of cells for BAL support.