Tetsutaro Hayashi

TL;DR: It is shown that single-cell Quartz-Seq can quantitatively detect various kinds of non-genetic cellular heterogeneity, and can detect different cell types and different cell-cycle phases of a single cell type.

TL;DR: It is proposed that Gomafu RNA represents a novel family of mRNA-like noncoding RNA that constitutes a cell-type-specific component of the nuclear matrix and remains intact after nuclear matrix preparation.

TL;DR: The novel and efficient algorithm SCODE is developed to infer regulatory networks from single‐cell RNA‐Seq during differentiation, based on ordinary differential equations, and it is confirmed that SCODE can reconstruct observed expression dynamics.

TL;DR: In this paper, a multicenter study comparing 13 commonly used scRNA-seq and single-nucleus RNA-seq protocols applied to a heterogeneous reference sample resource was conducted.

TL;DR: A new method to isolate the planarian adult stem cells as X‐ray‐sensitive cell populations by fluorescence‐activated cell sorting (FACS) is described, which may provide a key tool for advancing the understanding of the stem cell system in planarians.