T
Tetsutaro Sata
Researcher at National Institutes of Health
Publications - 328
Citations - 13513
Tetsutaro Sata is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Virus & Antigen. The author has an hindex of 60, co-authored 328 publications receiving 12582 citations. Previous affiliations of Tetsutaro Sata include Tokyo Medical and Dental University & Nagoya University.
Papers
More filters
Journal ArticleDOI
Modulation of TNF-α-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-α production and facilitates viral entry
Shiori Haga,Norio Yamamoto,Chikako Nakai-Murakami,Yoshiaki Osawa,Kenzo Tokunaga,Tetsutaro Sata,Naoki Yamamoto,Takehiko Sasazuki,Yukihito Ishizaka +8 more
TL;DR: It is found that the spike protein of SARS-CoV (SARS-S) induced TNF-α-converting enzyme (TACE)-dependent shedding of the ACE2 ectodomain, and this data suggest that cellular signals triggered by the interaction of Sars- coV with ACE2 are positively involved in viral entry but lead to tissue damage.
Journal ArticleDOI
Human APOBEC3F Is Another Host Factor That Blocks Human Immunodeficiency Virus Type 1 Replication
TL;DR: The human APOBEC3F protein is identified as another host factor that blocks human immunodeficiency virus type 1 (HIV-1) replication and induced G to A hypermutations in HIV genomic DNA, and the viral Vif protein counteracted its activity.
Journal ArticleDOI
Construction of an Excisable Bacterial Artificial Chromosome Containing a Full-Length Infectious Clone of Herpes Simplex Virus Type 1: Viruses Reconstituted from the Clone Exhibit Wild-Type Properties In Vitro and In Vivo
TL;DR: The infectious molecular clone pYEbac102 is in fact useful for mutagenesis of the HSV-1 genome by bacterial genetics, and a recombinant virus carrying amino acid substitutions in both copies of the α0 gene was generated.
Journal ArticleDOI
Naturally Acquired Plasmodium knowlesi Malaria in Human, Thailand
TL;DR: A case of naturally acquired infection with Plasmodium knowlesi in Thailand is described and diagnosis was confirmed by the small subunit ribosomal RNA and the mitochondrial cytochrome b sequences.
Journal ArticleDOI
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I
Hideki Hasegawa,Hirofumi Sawa,Martha J. Lewis,Martha J. Lewis,Yasuko Orba,Noreen Sheehy,Yoshie Yamamoto,Takeshi Ichinohe,Yasuko Tsunetsugu-Yokota,Harutaka Katano,Hidehiro Takahashi,Junichiro Matsuda,Tetsutaro Sata,Takeshi Kurata,Kazuo Nagashima,William W. Hall +15 more
TL;DR: The generation of HTLV-I Tax transgenic mice is described using the Lck proximal promoter to restrict transgene expression to developing thymocytes and this model accurately reproduces human disease and will provide a tool for analysis of the molecular events in transformation and for the development of new therapeutics.