W
William W. Hall
Researcher at University College Dublin
Publications - 218
Citations - 6657
William W. Hall is an academic researcher from University College Dublin. The author has contributed to research in topics: Virus & Viral load. The author has an hindex of 43, co-authored 203 publications receiving 6016 citations. Previous affiliations of William W. Hall include Global Virus Network & Trinity College, Dublin.
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Journal ArticleDOI
Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I
Hideki Hasegawa,Hirofumi Sawa,Martha J. Lewis,Martha J. Lewis,Yasuko Orba,Noreen Sheehy,Yoshie Yamamoto,Takeshi Ichinohe,Yasuko Tsunetsugu-Yokota,Harutaka Katano,Hidehiro Takahashi,Junichiro Matsuda,Tetsutaro Sata,Takeshi Kurata,Kazuo Nagashima,William W. Hall +15 more
TL;DR: The generation of HTLV-I Tax transgenic mice is described using the Lck proximal promoter to restrict transgene expression to developing thymocytes and this model accurately reproduces human disease and will provide a tool for analysis of the molecular events in transformation and for the development of new therapeutics.
Journal ArticleDOI
CD4 T Helper Type 1 and Regulatory T Cells Induced against the Same Epitopes on the Core Protein in Hepatitis C Virus- Infected Persons
Angus Macdonald,Margaret Duffy,Miriam T. Brady,Susan McKiernan,William W. Hall,John Hegarty,Michael P. Curry,Kingston H. G. Mills +7 more
TL;DR: It is demonstrated that T helper type 1 and regulatory T cells are induced against the same epitopes on the core protein during HCV infection.
Journal ArticleDOI
Proposal for diagnostic criteria of tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM)
Carlos Maurício de Castro-Costa,Abelardo Q.C. Araújo,Márcio M. Barreto,Osvaldo Massaiti Takayanagui,Marzia P. Sohler,Eduardo L. M. Da Silva,Sônia M. B. De Paula,Ricardo Ishak,João G. R. Ribas,Luis C. Rovirosa,Herwig Carton,Eduardo Gotuzzo,William W. Hall,Silvia M. Montano,Edward L. Murphy,Joel Oger,Carlos Remondegui,Graham P. Taylor +17 more
TL;DR: Brazilian neurologists and observers from other countries met recently to discuss and propose a modified model for diagnosing TSP/HAM with levels of ascertainment as definite, probable, and possible, according to myelopathic symptoms, serological findings, and/or detection of HTLV-I DNA and exclusion of other disorders.
Journal ArticleDOI
Human T-lymphotropic virus type II and neurological disease.
TL;DR: To evaluate the role of HTLV‐II in neurological disease, it is confirmed that although rare infection is associated with a disorder clinically similar or identical to HAM/TSP, neurologists should be aware of the potential clinical consequences of this infection.
Journal ArticleDOI
Updated European recommendations for the clinical use of HIV drug resistance testing
Anne-Mieke Vandamme,Anders Sönnerborg,Mounir Ait-Khaled,Jan Albert,Birgitta Åsjö,Lee T. Bacheler,Dénes Bánhegyi,Charles A. Boucher,Françoise Brun-Vézinet,Ricardo Jorge Camacho,P. Clevenbergh,Nathan Clumeck,N. Dedes,A. De Luca,Hans Wilhelm Doerr,Jean-Louis Faudon,Giorgio Gatti,Jan Gerstoft,William W. Hall,Angelos Hatzakis,Nicholas S. Hellmann,A Horban,Jens D Lundgren,Dale J. Kempf,Michael D. Miller,Veronica Miller,T. W. Myers,Claus Nielsen,Milos Opravil,Lucia Palmisano,Carlo Federico Perno,Andrew N. Phillips,Deenan Pillay,Tomás Pumarola,Lidia Ruiz,Mika Salminen,Jonathan M. Schapiro,Barbara Schmidt,Jean-Claude Schmit,Rob Schuurman,E. Shulse,Vincent Soriano,Schlomo Staszewski,Stefano Vella,M Youle,Rainer Ziermann,Luc Perrin +46 more
TL;DR: The European HIV Drug Resistance Panel was established to make recommendations to clinicians and virologists on this topic and to propose quality control measures as mentioned in this paper, and the panel recommended resistance testing for the following indications: i) drug-naive patients with acute or recent infection; ii) therapy failure, including suboptimal treatment response, when treatment change is considered; iii) pregnant HIV-1-infected women and paediatric patients with detectable viral load when treatment initiation or change is considering; and iv) genotype source patient when post-exposure prophylaxis is considered