T
Thanh Tung Pham
Researcher at Yeungnam University
Publications - 7
Citations - 195
Thanh Tung Pham is an academic researcher from Yeungnam University. The author has contributed to research in topics: Cancer & Antigen. The author has an hindex of 4, co-authored 5 publications receiving 101 citations.
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Journal ArticleDOI
Tumor-targeting, pH-sensitive nanoparticles for docetaxel delivery to drug-resistant cancer cells.
Tuan Hiep Tran,Thiruganesh Ramasamy,Ju Yeon Choi,Hanh Thuy Nguyen,Thanh Tung Pham,Jee-Heon Jeong,Sae-Kwang Ku,Han-Gon Choi,Chul Soon Yong,Jong Oh Kim +9 more
TL;DR: In vivo anticancer effect of DTX-LPH nanoparticles was further confirmed by the elevated levels of caspase-3 and poly ADP ribose polymerase found in the tumors after treatment.
Journal ArticleDOI
Anti-CTLA-4 antibody-functionalized dendritic cell-derived exosomes targeting tumor-draining lymph nodes for effective induction of antitumor T-cell responses.
Cao Dai Phung,Thanh Tung Pham,Hanh Thuy Nguyen,Tien Tiep Nguyen,Wenquan Ou,Jee-Heon Jeong,Han-Gon Choi,Sae-Kwang Ku,Chul Soon Yong,Jong Oh Kim +9 more
TL;DR: This study provides a unique strategy for functionalizing exosome membrane with anti-CTLA-4 antibody via lipid-anchoring method to synergize efficacy of cancer vaccination and immune checkpoint blockade against the tumor.
Journal ArticleDOI
Reprogramming the T cell response to cancer by simultaneous, nanoparticle-mediated PD-L1 inhibition and immunogenic cell death
Cao Dai Phung,Hanh Thuy Nguyen,Ju Yeon Choi,Thanh Tung Pham,Suman Acharya,Maheshwor Timilshina,Jae-Hoon Chang,Ju Hyun Kim,Jee-Heon Jeong,Sae-Kwang Ku,Han-Gon Choi,Chul Soon Yong,Jong Oh Kim +12 more
TL;DR: The results suggest that simultaneous PD-L1 inhibition via microRNAs and the induction of an immunogenic tumor microenvironment via low-dose cytotoxic drugs may improve cancer therapy efficacy.
Journal ArticleDOI
Targeting and clearance of senescent foamy macrophages and senescent endothelial cells by antibody-functionalized mesoporous silica nanoparticles for alleviating aorta atherosclerosis.
Le Minh Pham,Eok-Cheon Kim,Wenquan Ou,Cao Dai Phung,Tien Tiep Nguyen,Thanh Tung Pham,Kishwor Poudel,Milan Gautam,Hanh Thuy Nguyen,Jee-Heon Jeong,Chul Soon Yong,So-Young Park,Jae-Ryong Kim,Jong Oh Kim +13 more
TL;DR: In this article, a CD9 antibody-modified mesoporous silica nanoparticles with a hyaluronidase-responsive drug release profile was developed for mitigating atherosclerosis through senescent cell clearance.
Journal ArticleDOI
Engineering New Immunotherapies against Cancer using Bacterial Outer Membrane Vesicles and Supported by Preclinical Data
James E. Galen,Thanh Tung Pham +1 more
TL;DR: Current research using purified rOMVs as immunotherapeutic vaccines is summarized and potential obstacles that still need to be adequately addressed are discussed to ensure success in human trials.