T
Theresa J. O'Halloran
Researcher at University of Texas at Austin
Publications - 19
Citations - 944
Theresa J. O'Halloran is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Clathrin & Clathrin adaptor proteins. The author has an hindex of 15, co-authored 19 publications receiving 868 citations. Previous affiliations of Theresa J. O'Halloran include University of Iowa & Louisiana State University.
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Journal ArticleDOI
Talin at myotendinous junctions
TL;DR: Electron microscopic immunolabeling shows talin is a component of the digitlike processes of muscle cells that extend into tendons at myotendinous junctions, indicating that there may be similarities in the molecular composition of focal contacts and myotendedinous junications in addition to functional analogies.
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Mechanisms of nuclear content loading to exosomes
Akira Yokoi,Alejandro Villar-Prados,Alejandro Villar-Prados,Paul A. Oliphint,Jianhua Zhang,Xingzhi Song,Peter De Hoff,Robert Morey,Jinsong Liu,Jason Roszik,Karen Clise-Dwyer,Jared K. Burks,Theresa J. O'Halloran,Louise C. Laurent,Anil K. Sood +14 more
TL;DR: This work identifies the relationship between cancer cell micronuclei (MN), which are markers of genomic instability, and nExo formation and observes that multivesicular body precursors and exosomal markers, such as the tetraspanins, directly interact with MN.
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A novel role for clathrin in cytokinesis
TL;DR: It is demonstrated that clathrin is essential for construction of a functional contractile ring during cell division, and specific for cytokinesis.
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Clathrin heavy chain functions in sorting and secretion of lysosomal enzymes in Dictyostelium discoideum.
TL;DR: The study of the mutant cells provide in vivo evidence for roles for the clathrin heavy chain in the internalization of fluid from the plasma membrane; sorting of hydrolase precursors from the constitutive secretory pathway to the lysosomal pathway; and secretion of mature hydrolases from lysOSomes to the extracellular space.
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Cytokinesis failure in clathrin-minus cells is caused by cleavage furrow instability
TL;DR: It is found that adherent clathrin null cells do form cleavage furrows but cannot maintain a consistent rate of furrow ingression, and it is postulate that this morphology is the result of contraction at the rear of the presumptive daughter cells in concert with incomplete furrows ingression.