J
Jinsong Liu
Researcher at University of Texas MD Anderson Cancer Center
Publications - 302
Citations - 21899
Jinsong Liu is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 79, co-authored 266 publications receiving 19296 citations. Previous affiliations of Jinsong Liu include Case Western Reserve University & University of Texas Health Science Center at Houston.
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Journal ArticleDOI
The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo.
TL;DR: It is reported here that mice deficient in the mPer2 gene are cancer prone and suggested that the m per2 gene functions in tumor suppression by regulating DNA damage-responsive pathways.
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The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers
Kwai Wa Cheng,John P. Lahad,Wen Lin Kuo,Anna Lapuk,Kyosuke Yamada,Nelly Auersperg,Jinsong Liu,Karen Smith-McCune,Karen H. Lu,David A. Fishman,Joe W. Gray,Gordon B. Mills +11 more
TL;DR: These studies implicate RAB25, and thus the RAB family of small G proteins, in aggressiveness of epithelial cancers.
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Selection of Potential Markers for Epithelial Ovarian Cancer with Gene Expression Arrays and Recursive Descent Partition Analysis
Karen H. Lu,Andrea P. Patterson,Lin Wang,Rebecca T. Marquez,Edward N. Atkinson,Keith A. Baggerly,Lance R. Ramoth,Daniel G. Rosen,Jinsong Liu,Ingegerd Hellstrom,David I. Smith,Lynn C. Hartmann,David A. Fishman,Andrew Berchuck,Rosemarie Schmandt,Regina S. Whitaker,David M. Gershenson,Gordon B. Mills,Robert C. Bast +18 more
TL;DR: The data are consistent with the possibility that a limited number of markers in combination might identify >99% of epithelial ovarian cancers despite the heterogeneity of the disease.
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Potential markers that complement expression of CA125 in epithelial ovarian cancer
Daniel G. Rosen,Lin Wang,J. Neeley Atkinson,Yinhua Yu,Karen H. Lu,Eleftherios P. Diamandis,Ingegerd Hellström,Samuel C. Mok,Jinsong Liu,Robert C. Bast +9 more
TL;DR: At the level of tissue expression, each of 10 potential serum markers could be detected in 29-100% of ovarian cancers that had low or absent expression of CA125.
Journal ArticleDOI
Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer
Da Yang,Yan Sun,Yan Sun,Limei Hu,Hong Zheng,Hong Zheng,Ping Ji,Chad V. Pecot,Yanrui Zhao,Sheila Reynolds,Hanyin Cheng,Rajesha Rupaimoole,David Cogdell,Matti Nykter,Russell Broaddus,Cristian Rodriguez-Aguayo,Gabriel Lopez-Berestein,Jinsong Liu,Ilya Shmulevich,Anil K. Sood,Kexin Chen,Wei Zhang +21 more
TL;DR: Integrated genomic analyses revealed a miRNA-regulatory network that further defined a robust integrated mesenchymal subtype associated with poor overall survival in serous ovarian cancer (OvCa) and predicted eight key miRNAs were predicted to regulate 89% of the targets in this network.