T
Thomas Abeel
Researcher at Delft University of Technology
Publications - 96
Citations - 10940
Thomas Abeel is an academic researcher from Delft University of Technology. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 27, co-authored 81 publications receiving 8039 citations. Previous affiliations of Thomas Abeel include Ghent University & Flanders Institute for Biotechnology.
Papers
More filters
Journal ArticleDOI
ORCAE: online resource for community annotation of eukaryotes
TL;DR: ORCAE as discussed by the authors is an online annotation tool for gene annotation, where the quality of the presented annotation is the responsibility of the whole community and several automatic checks have been put in place that encompass all existing knowledge on the gene structure and functions.
Journal ArticleDOI
Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance
Christopher A. Desjardins,Keira A. Cohen,Keira A. Cohen,Vanisha Munsamy,Thomas Abeel,Thomas Abeel,Kashmeel Maharaj,Bruce J. Walker,Terrance Shea,Deepak V. Almeida,Abigail L. Manson,Alex N. Salazar,Alex N. Salazar,Nesri Padayatchi,Max R. O'Donnell,Max R. O'Donnell,Koleka Mlisana,Koleka Mlisana,Jennifer R. Wortman,Bruce W. Birren,Jacques H. Grosset,Ashlee M. Earl,Alexander S. Pym +22 more
TL;DR: It is found that loss-of-function mutations in ald (Rv2780), encoding L-alanine dehydrogenase, were associated with unexplained drug resistance, and drug susceptibility testing established that ald loss of function conferred resistance to D-cycloserine, and susceptibility to the drug was partially restored by complementation of ald.
Journal ArticleDOI
Nanopore sequencing enables near-complete de novo assembly of Saccharomyces cerevisiae reference strain CEN.PK113-7D.
Alex N. Salazar,Alex N. Salazar,Arthur R. Gorter de Vries,Marcel van den Broek,Melanie Wijsman,Pilar de la Torre Cortés,Anja Brickwedde,Nick Brouwers,Jean-Marc Daran,Thomas Abeel,Thomas Abeel +10 more
TL;DR: The power of long‐read sequencing is demonstrated by providing a high‐quality reference assembly and annotation of CEN.PK113‐7D and places a caveat on assumed genome stability of microorganisms.
Journal ArticleDOI
GenomeView: a next-generation genome browser
TL;DR: GenomeView is a stand-alone genome browser specifically designed to visualize and manipulate a multitude of genomics data, unique in its capability to interactively handle huge data sets consisting of tens of aligned genomes, thousands of annotation features and millions of mapped short reads both as viewer and editor.
Journal ArticleDOI
Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development.
Jason W. Holder,Jil C. Ulrich,Anthony C. DeBono,Paul A. Godfrey,Christopher A. Desjardins,Jeremy Zucker,Jeremy Zucker,Qiandong Zeng,Alex L. B. Leach,Ion Ghiviriga,Christine Dancel,Thomas Abeel,Dirk Gevers,Chinnappa D. Kodira,Brian Desany,Jason P. Affourtit,Bruce W. Birren,Anthony J. Sinskey +17 more
TL;DR: In this paper, a comparative analysis of the 9.27 Mb R. opacus PD630 genome was performed and the results of the catabolic screen, phylogenetic analysis of TAGs cycle enzymes, and metabolic product characterizations were integrated into a working model of prokaryotic oleaginy.