T
Thomas Baukrowitz
Researcher at University of Kiel
Publications - 63
Citations - 5169
Thomas Baukrowitz is an academic researcher from University of Kiel. The author has contributed to research in topics: Gating & Potassium channel. The author has an hindex of 35, co-authored 60 publications receiving 4846 citations. Previous affiliations of Thomas Baukrowitz include University of Jena & University of Oxford.
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Journal ArticleDOI
The inward rectification mechanism of the HERG cardiac potassium channel
TL;DR: The characteristics of this gating suggest a specific role for this channel in the normal suppression of arrhythmias, and the inactivation gating mechanism resembles that of C-type inactivation of K+ channels.
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PIP2 and PIP as Determinants for ATP Inhibition of KATP Channels
Thomas Baukrowitz,Uwe Schulte,Dominik Oliver,Stefan Herlitze,Tobias Krauter,Stephen J. Tucker,J. Peter Ruppersberg,Bernd Fakler +7 more
TL;DR: It is reported here that phosphatidylinositol-4, 5-bisphosphate (PIP2) and phosphorus-4-phosphates(PIP) controlled ATP inhibition of cloned KATP channels (Kir6.2 and SUR1) and represents a mechanism for control of excitability through phospholipids.
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Modulation of K+ current by frequency and external [K+]: A tale of two inactivation mechanisms
Thomas Baukrowitz,Gary Yellen +1 more
TL;DR: It is found that frequency-dependent cumulative inactivation of Shaker channels is very sensitive to changes of extracellular K+ in the physiological range, with much more inactivation at low [K+]out, and that it results from the interaction of N- and C-type inactivation.
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Functional Conversion Between A-Type and Delayed Rectifier K+ Channels by Membrane Lipids
TL;DR: It is shown that membrane lipids can convert A-type channels into delayed rectifiers and vice versa and that bidirectional control of Kv channel gating by lipids may provide a mechanism for the dynamic regulation of electrical signaling in the nervous system.
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Gating of Ca2+-activated K+ channels controls fast inhibitory synaptic transmission at auditory outer hair cells.
Dominik Oliver,Nikolaj Klöcker,Jochen Schuck,Thomas Baukrowitz,J. Peter Ruppersberg,Bernd Fakler +5 more
TL;DR: It is shown here that unitary inhibitory postsynaptic currents at this synapse are mediated by SK2 channels and occur rapidly, with rise and decay time constants of approximately 6 ms and approximately 30 ms, respectively.