T
Thomas G Brewer
Researcher at University of Washington
Publications - 11
Citations - 1803
Thomas G Brewer is an academic researcher from University of Washington. The author has contributed to research in topics: Environmental enteropathy & Population. The author has an hindex of 9, co-authored 11 publications receiving 1204 citations. Previous affiliations of Thomas G Brewer include Bill & Melinda Gates Foundation.
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Journal ArticleDOI
Rotavirus Vaccination and the Global Burden of Rotavirus Diarrhea Among Children Younger Than 5 Years.
Christopher Troeger,Ibrahim A Khalil,Puja C Rao,Shujin Cao,Brigette F. Blacker,Tahmeed Ahmed,George Armah,Julie E Bines,Julie E Bines,Thomas G Brewer,Danny V. Colombara,Gagandeep Kang,Beth D. Kirkpatrick,Carl D. Kirkwood,Jason M. Mwenda,Umesh D. Parashar,William A. Petri,Mark S Riddle,A. Duncan Steele,Robert L. Thompson,Judd L. Walson,John W. Sanders,Ali H. Mokdad,Christopher J L Murray,Simon I. Hay,Simon I. Hay,Robert Reiner +26 more
TL;DR: It is suggested that prioritizing vaccine introduction and interventions to reduce diarrhea-associated morbidity and mortality is necessary in the continued global reduction of rotavirus infection.
Journal ArticleDOI
Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016.
Ibrahim A Khalil,Christopher Troeger,Brigette F. Blacker,Puja C Rao,Alexandria Brown,Deborah Atherly,Thomas G Brewer,Cyril Engmann,Cyril Engmann,Eric R. Houpt,Gagandeep Kang,Karen L. Kotloff,Myron M. Levine,Stephen P. Luby,Calman A. MacLennan,William Pan,William Pan,Patricia B Pavlinac,James A Platts-Mills,Firdausi Qadri,Mark S. Riddle,Edward T. Ryan,David A Shoultz,A. Duncan Steele,Judd L. Walson,John W. Sanders,Ali H. Mokdad,Christopher J L Murray,Simon I. Hay,Simon I. Hay,Robert Reiner +30 more
TL;DR: The global burden of shigella and ETEC diarrhoea according to age, sex, geography, and year from 1990 to 2016 is analyzed to assess the health burden of bacterial diarrhoeal pathogens globally.
Journal ArticleDOI
Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study
Ibrahim A Khalil,Christopher Troeger,Puja C Rao,Brigette F. Blacker,Alexandria Brown,Thomas G Brewer,Danny V. Colombara,Eugenio L. de Hostos,Cyril Engmann,Cyril Engmann,Richard L. Guerrant,Rashidul Haque,Eric R. Houpt,Gagandeep Kang,Poonum S. Korpe,Karen L. Kotloff,Aldo A. M. Lima,William A. Petri,James A Platts-Mills,David A Shoultz,Mohammad H. Forouzanfar,Simon I. Hay,Simon I. Hay,Robert Reiner,Ali H. Mokdad +24 more
TL;DR: It is estimated that diarrhoea from Cryptosporidium infection caused an additional 7·85 million disability-adjusted life-years after the authors accounted for its effect on growth faltering—153% more than that estimated from acute effects alone.
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Environmental Enteric Dysfunction: Pathogenesis, Diagnosis, and Clinical Consequences
Gerald T. Keusch,Donna M. Denno,Robert E. Black,Christopher Duggan,Richard L. Guerrant,James V. Lavery,James P. Nataro,Irwin H. Rosenberg,Edward T. Ryan,Phillip I. Tarr,Honorine D. Ward,Zulfiqar A Bhutta,Hoosen Coovadia,Aldo A. M. Lima,Balakrishnan S. Ramakrishna,Anita K. M. Zaidi,Deborah C. Hay Burgess,Thomas G Brewer +17 more
TL;DR: In this article, the authors provide recommendations to define and validate a working clinical diagnosis and to guide critical research in this area to effectively proceed, and provide recommendations for early gut functional changes and inflammation may preclude or mitigate the later adverse vicious cycle of malnutrition and infection.
Journal ArticleDOI
Implications of Acquired Environmental Enteric Dysfunction for Growth and Stunting in Infants and Children Living in Low- and Middle-Income Countries
Gerald T. Keusch,Irwin H. Rosenberg,Donna M. Denno,Christopher Duggan,Richard L. Guerrant,James V. Lavery,Philip I. Tarr,Honorine D. Ward,Robert E. Black,James P. Nataro,Edward T. Ryan,Zulfiqar A Bhutta,Hoosen Coovadia,Aldo A. M. Lima,Balakrishnan S. Ramakrishna,Anita K. M. Zaidi,Deborah Hay C. Burgess,Thomas G Brewer +17 more
TL;DR: Changes in small bowel function early in infancy in developing countries are increasingly being demonstrated, probably accompanied by altered mucosal architecture in most individuals, including reduced enterocyte mass and evidence of immune activation and inflammation in the mucosa, which may be a cause of growth faltering and stunting in young children.