T
Thomas Sainte-Luce Banchelin
Researcher at Umeå University
Publications - 8
Citations - 180
Thomas Sainte-Luce Banchelin is an academic researcher from Umeå University. The author has contributed to research in topics: Enantioselective synthesis & Pyridine. The author has an hindex of 5, co-authored 8 publications receiving 172 citations. Previous affiliations of Thomas Sainte-Luce Banchelin include ACADIA Pharmaceuticals Inc. & University of Gothenburg.
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Journal ArticleDOI
Efficient, mild and completely regioselective synthesis of substituted pyridines
Hans Andersson,Thomas Sainte-Luce Banchelin,Sajal Das,Roger Olsson,Roger Olsson,Fredrik Almqvist +5 more
TL;DR: Addition of Grignard reagents to pyridine N-oxides in THF at low temperature and treatment with TFAA provides an efficient general procedure for synthesis of substituted pyridines.
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Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure–activity study
Erik Chorell,Jerome S. Pinkner,Christoffer Bengtsson,Thomas Sainte-Luce Banchelin,Sofie Edvinsson,Anna Linusson,Scott J. Hultgren,Fredrik Almqvist +7 more
TL;DR: A comprehensive structure activity relationship (SAR) study of the dihydrothiazolo ring-fused 2-pyridone pilicide central fragment by varying all open positions resulted in both highly valuable SAR information and potent inhibitors of type 1 pili dependent biofilm formation.
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Complete regioselective addition of grignard reagents to pyrazine N-oxides, toward an efficient enantioselective synthesis of substituted piperazines.
Hans Andersson,Thomas Sainte-Luce Banchelin,Sajal Das,Magnus Gustafsson,Roger Olsson,Fredrik Almqvist +5 more
TL;DR: A conceptually new one-pot strategy for the synthesis of protected substituted piperazines via the addition of Grignard reagents to pyrazine N-oxides is presented and is high yielding, step-efficient, and fast.
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Enantioselective synthesis of substituted piperidines by addition of aryl Grignard reagents to pyridine N-oxides
TL;DR: The synthesis of optically active piperidines by enantioselective addition of aryl Grignard reagents to pyridine N-oxides and lithium binolate followed by reduction is reported for the first time.
Journal ArticleDOI
Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity
Erik Chorell,Christoffer Bengtsson,Thomas Sainte-Luce Banchelin,Pralay Das,Hanna Uvell,Arun K. Sinha,Jerome S. Pinkner,Scott J. Hultgren,Fredrik Almqvist +8 more
TL;DR: A new synthetic platform has been developed that enables fast and simple introduction of various substituents in position C-7 on the peptidomimetic scaffold and enables introduction of previously unattainable heteroatoms in this position.