T
Thu Han Nguyen
Researcher at Scripps Research Institute
Publications - 1
Citations - 104
Thu Han Nguyen is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Gliotoxin & Diketopiperazines. The author has an hindex of 1, co-authored 1 publications receiving 92 citations.
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Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents.
Kyriacos C. Nicolaou,Min Lu,Sotirios Totokotsopoulos,Philipp Heretsch,Denis Giguère,Ya Ping Sun,David Sarlah,Thu Han Nguyen,Ian Coulter Wolf,Donald F. Smee,Craig W. Day,Selina Bopp,Elizabeth A. Winzeler +12 more
TL;DR: Biological screening of selected synthesized compounds led to the discovery of a number of nanomolar antipoliovirus agents and several low-micromolar anti- Plasmodium falciparum lead compounds.