T
Tianwei Yu
Researcher at Emory University
Publications - 166
Citations - 6701
Tianwei Yu is an academic researcher from Emory University. The author has contributed to research in topics: Computer science & Engineering. The author has an hindex of 38, co-authored 132 publications receiving 5577 citations. Previous affiliations of Tianwei Yu include The Chinese University of Hong Kong & University of Illinois at Chicago.
Papers
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Journal ArticleDOI
Incorporating Nonlinear Relationships in Microarray Missing Value Imputation
Tianwei Yu,Hesen Peng,Wei Sun +2 more
TL;DR: By simulations based on real microarray data, it is shown that incorporating nonlinear relationships could improve the accuracy of missing value imputation, both in terms of normalized root-mean-squared error and in the preservation of the list of significant genes in statistical testing.
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Global Gene Expression Profiling of Endothelium Exposed to Heme Reveals an Organ-Specific Induction of Cytoprotective Enzymes in Sickle Cell Disease
Samit Ghosh,Fang Tan,Tianwei Yu,Yuhua Li,Olufolake Adisa,Mario Mosunjac,Solomon F. Ofori-Acquah +6 more
TL;DR: Individual organ systems induce unique profiles of cytoprotective enzymes to neutralize heme in SCD, and understanding this heterogeneity may help to develop effective therapies to manage vasculopathies of individual systems.
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Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood.
Mohammed Ata Ur Rasheed,Carole J. Hickman,Marcia McGrew,Sun B. Sowers,Sara Mercader,Amy Hopkins,Vickie Grimes,Tianwei Yu,Jens Wrammert,Mark J. Mulligan,William J. Bellini,Paul A. Rota,Walter A. Orenstein,Rafi Ahmed,Srilatha Edupuganti +14 more
TL;DR: Blood samples from 71 healthy 18- to 23-year-old college students living in a non-outbreak area were assayed for antibodies and memory B cells to mumps, measles, and rubella, and the index standard ratio indicated that the concentration of IgG was significantly lower for mumps than rubella.
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Local false discovery rate estimation using feature reliability in LC/MS metabolomics data
Elizabeth Y. Chong,Yijian Huang,Hao Wu,Nima Ghasemzadeh,Karan Uppal,Arshed A. Quyyumi,Dean P. Jones,Tianwei Yu +7 more
TL;DR: A reliability index for mass spectrometry-based metabolomics data with repeated measurements is proposed, which is quantified using a composite measure and applied to a real metabolomics dataset and was able to detect more differentially expressed metabolites that were biologically meaningful.
Journal ArticleDOI
Reactivation and refolding of a partially folded creatine kinase modified by 5,5'-dithio-bis(2-nitrobenzoic acid).
TL;DR: In the presence of DTT, the partially folded modified creatine kinase can be reactivated and refolded following a biphasic course, suggesting the existence of a monomeric intermediate during the refolding of CK.