T
Tim James
Researcher at University of Oxford
Publications - 123
Citations - 4569
Tim James is an academic researcher from University of Oxford. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 26, co-authored 99 publications receiving 3071 citations. Previous affiliations of Tim James include John Radcliffe Hospital.
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Journal ArticleDOI
Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers.
Sheila F Lumley,Denise O'Donnell,Nicole Stoesser,Philippa C Matthews,Alison Howarth,Stephanie B Hatch,Brian D. Marsden,Stuart Cox,Tim James,Fiona Warren,Liam J Peck,Thomas G Ritter,Z de Toledo,Laura Warren,David Axten,Richard J. Cornall,E Y Jones,David I. Stuart,Gavin R. Screaton,Daniel Ebner,Sarah Hoosdally,Sarah Hoosdally,Meera Chand,D W Crook,D W Crook,O'Donnell A-M.,Christopher P. Conlon,Koen B. Pouwels,A S Walker,A S Walker,Peto Tea.,Susan Hopkins,Timothy M Walker,Katie Jeffery,David W Eyre +34 more
TL;DR: The relationship between the presence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the risk of subsequent reinfection remains unclear as discussed by the authors.
Journal ArticleDOI
Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison
Mark A. Ainsworth,Monique Andersson,Monique Andersson,Kathryn Auckland,J K Baillie,Eleanor Barnes,Sally Beer,A Beveridge,Sadia Bibi,L Blackwell,M Borak,Abbie Bown,Tim Brooks,Nicola A. Burgess-Brown,S Camara,Matthew Catton,K K Chau,Thomas Christott,Elizabeth A. Clutterbuck,Jesse Coker,Richard J. Cornall,Stuart Cox,D Crawford-Jones,Derrick W. Crook,Silvia D'Arcangelo,W Dejnirattsai,Dequaire Jmm.,S Dimitriadis,Kate E. Dingle,George Doherty,Christina Dold,Tao Dong,Susanna Dunachie,Daniel Ebner,M Emmenegger,A Espinosa,David W Eyre,Rory Fairhead,S Fassih,Conor Feehily,S Felle,Alejandra Fernández-Cid,M Fernandez Mendoza,T H Foord,T Fordwoh,D Fox McKee,John Frater,V Gallardo Sanchez,N Gent,D Georgiou,Christopher J. Groves,Bassam Hallis,P M Hammond,Stephanie B Hatch,Heli Harvala,Jennifer Hill,Sarah Hoosdally,B Horsington,Alison Howarth,Tim James,Katie Jeffery,E Y Jones,Anita Justice,F Karpe,James Kavanagh,D S Kim,R Kirton,Paul Klenerman,Julian C. Knight,L Koukouflis,Andrew J Kwok,U Leuschner,R Levin,A Linder,T Lockett,Sheila F Lumley,S Marinou,Brian D. Marsden,José William Martínez,L Martins Ferreira,L Mason,Philippa C Matthews,Alexander J. Mentzer,A Mobbs,Juthathip Mongkolsapaya,J Morrow,Mukhopadhyay Smm.,Matt J. Neville,Sarah Oakley,Marta Oliveira,Ashley Otter,K Paddon,J Pascoe,Y Peng,E Perez,Prem Perumal,Peto Tea.,H Pickford,Rutger J. Ploeg,Andrew J. Pollard,Alex J. Richardson,Thomas G Ritter,Devender Roberts,Gillian Rodger,Christine S. Rollier,Cathy Rowe,Justine K. Rudkin,Gavin R. Screaton,Malcolm G Semple,Alex Sienkiewicz,L Silva-Reyes,Donal T. Skelly,A Sobrino Diaz,L Stafford,Lisa Stockdale,Nicole Stoesser,Teresa L Street,David I. Stuart,Angela Sweed,Aimee R. Taylor,H Thraves,H P Tsang,M K Verheul,Richard Vipond,Timothy M Walker,Susan Wareing,Y Warren,Carrow I. Wells,C Wilson,K Withycombe,R K Young +130 more
TL;DR: Four commercial, widely available assays and a scalable 384-well ELISA can be used for SARS-CoV-2 serological testing to achieve sensitivity and specificity of at least 98%.
Journal ArticleDOI
Advantages of normothermic perfusion over cold storage in liver preservation.
Charles Imber,Shawn D. St. Peter,Inigo Lopez De Cenarruzabeitia,Dave Pigott,Tim James,Richard G. Taylor,James Mcguire,David P. Hughes,Andrew J. Butler,Michael A. Rees,Peter J. Friend +10 more
TL;DR: Normothermic sanguineous oxygenated perfusion is a superior method of preservation compared with simple cold storage in UW solution and allows the possibility to assess viability of the graft before transplantation.
Journal ArticleDOI
Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study.
David W Eyre,Sheila F Lumley,Denise O'Donnell,Mark Campbell,Elizabeth Sims,Elaine Lawson,Fiona Warren,Tim James,Stuart Cox,Alison Howarth,George Doherty,Stephanie B Hatch,James Kavanagh,Kevin K Chau,Philip W. Fowler,Jeremy Swann,Denis Volk,Fan Yang-Turner,Nicole Stoesser,Philippa C Matthews,Maria Dudareva,Tim Davies,Robert Shaw,Leon Peto,Louise O Downs,Alexander Vogt,Ali Amini,Bernadette C. Young,Philip G. Drennan,Alexander J. Mentzer,Donal T. Skelly,Fredrik Karpe,Matt J. Neville,Monique Andersson,Andrew Brent,Nick S. Jones,L Martins Ferreira,Thomas Christott,Brian D. Marsden,Sarah Hoosdally,Richard J. Cornall,Derrick W. Crook,David I. Stuart,Gavin R. Screaton,T Peto,Bruno Holthof,O'Donnell A-M.,Daniel Ebner,Christopher P. Conlon,Katie Jeffery,Timothy M Walker +50 more
TL;DR: Risks were heterogenous across the hospital, with higher rates in acute medicine, and sporadic outbreaks in areas with few or no Covid-19 patients.
Journal ArticleDOI
The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers.
Sheila F Lumley,Jia Wei,Denise O'Donnell,Nicole Stoesser,Nicole Stoesser,Nicole Stoesser,Philippa C Matthews,Philippa C Matthews,Philippa C Matthews,Alison Howarth,Stephanie B Hatch,Brian D. Marsden,Stuart Cox,Tim James,Liam J Peck,Thomas G Ritter,Z de Toledo,Richard J. Cornall,E Y Jones,David I. Stuart,Gavin R. Screaton,Daniel Ebner,Sarah Hoosdally,Sarah Hoosdally,Sarah Hoosdally,Derrick W. Crook,Derrick W. Crook,Derrick W. Crook,Christopher P. Conlon,Koen B. Pouwels,Koen B. Pouwels,A S Walker,A S Walker,A S Walker,Peto Tea.,Peto Tea.,Peto Tea.,Timothy M Walker,Katie Jeffery,David W Eyre +39 more
TL;DR: IgG antibody levels to SARS-CoV-2 nucleocapsid wane within months, and faster in younger adults and those without symptoms, while increasing age, Asian ethnicity and prior self-reported symptoms were independently associated with higher maximum antibody levels.