R
Richard J. Cornall
Researcher at University of Oxford
Publications - 123
Citations - 11613
Richard J. Cornall is an academic researcher from University of Oxford. The author has contributed to research in topics: B cell & Antigen. The author has an hindex of 46, co-authored 113 publications receiving 9423 citations. Previous affiliations of Richard J. Cornall include Medical Research Council & John Radcliffe Hospital.
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Journal ArticleDOI
Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.
Yanchun Peng,Alexander J. Mentzer,G Liu,G Liu,X Yao,Z Yin,D Dong,D Dong,Wanwisa Dejnirattisai,T Rostron,P Supasa,C Liu,Cesar Lopez-Camacho,J Slon-Campos,Yuguang Zhao,David I. Stuart,Guido C. Paesen,Jonathan M. Grimes,Alfred A. Antson,Oliver W. Bayfield,Hawkins Dedp.,Ker D-S.,B Wang,Lance Turtle,Krishanthi Subramaniam,Paul Thomson,P Zhang,Christina Dold,Jeremy Ratcliff,Peter Simmonds,T I de Silva,Paul Sopp,Dannielle Wellington,U S Rajapaksa,Chen Y-L.,Mariolina Salio,Giorgio Napolitani,Wayne Paes,Persephone Borrow,Benedikt M. Kessler,J W Fry,N F Schwabe,Malcolm G Semple,Malcolm G Semple,J K Baillie,Shona C Moore,Openshaw Pjm.,M A Ansari,Susanna Dunachie,Eleanor Barnes,John Frater,G Kerr,Philip J. R. Goulder,T Lockett,R Levin,Y Zhang,Y Zhang,R Jing,Ho L-P.,Richard J. Cornall,Christopher P. Conlon,Paul Klenerman,Gavin R. Screaton,Juthathip Mongkolsapaya,Andrew J. McMichael,Julian C. Knight,Graham S. Ogg,Tao Dong +67 more
TL;DR: The identification of T cell responses associated with milder disease will support an understanding of protective immunity and highlights the potential of including non-spike proteins within future COVID-19 vaccine design.
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A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
Carola G. Vinuesa,Matthew C. Cook,Constanza Angelucci,Vicki Athanasopoulos,Lixin Rui,Kim M. Hill,Di Yu,Heather Domaschenz,Belinda Whittle,Teresa Lambe,Ian Roberts,Richard R. Copley,John I. Bell,Richard J. Cornall,Christopher C. Goodnow +14 more
TL;DR: The mouse genome is systematically screened for autoimmune regulators to isolate a mouse strain, sanroque, with severe autoimmune disease resulting from a single recessive defect in a previously unknown mechanism for repressing antibody responses to self.
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Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers.
Sheila F Lumley,Denise O'Donnell,Nicole Stoesser,Philippa C Matthews,Alison Howarth,Stephanie B Hatch,Brian D. Marsden,Stuart Cox,Tim James,Fiona Warren,Liam J Peck,Thomas G Ritter,Z de Toledo,Laura Warren,David Axten,Richard J. Cornall,E Y Jones,David I. Stuart,Gavin R. Screaton,Daniel Ebner,Sarah Hoosdally,Sarah Hoosdally,Meera Chand,D W Crook,D W Crook,O'Donnell A-M.,Christopher P. Conlon,Koen B. Pouwels,A S Walker,A S Walker,Peto Tea.,Susan Hopkins,Timothy M Walker,Katie Jeffery,David W Eyre +34 more
TL;DR: The relationship between the presence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the risk of subsequent reinfection remains unclear as discussed by the authors.
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Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.
Chad K. Heazlewood,Matthew C. Cook,Rajaraman Eri,Gareth Price,Sharyn B. Tauro,Douglas Taupin,David J. Thornton,Chin Wen Png,Tanya L. Crockford,Richard J. Cornall,Rachel J. Adams,Masato Kato,Keats Nelms,Nancy A. Hong,Timothy H. Florin,Christopher C. Goodnow,Michael A. McGuckin +16 more
TL;DR: It is demonstrated that mucin misfolding and ER stress initiate colitis in mice, and that ER stress-related mucin depletion could be a fundamental component of the pathogenesis of human colitis and that clinical studies combining genetics, ER stressed pathology and relevant environmental epidemiology are warranted.
Journal ArticleDOI
Genetic analysis of autoimmune type 1 diabetes mellitus in mice.
John A. Todd,T J Aitman,Richard J. Cornall,S Ghosh,Jennifer Ruth Sadler Hall,C M Hearne,Andrew M. Knight,Jennifer M. Love,M A McAleer,Jan-Bas Prins +9 more
TL;DR: In this article, a genetic map of the mouse genome, analysed using the polymerase chain reaction, has been assembled specifically for the study of autoimmune type 1 diabetes in the nonobese diabetic mouse.