T
Timo Laaksonen
Researcher at University of Helsinki
Publications - 120
Citations - 6363
Timo Laaksonen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Drug delivery & Cellulose. The author has an hindex of 39, co-authored 113 publications receiving 5574 citations. Previous affiliations of Timo Laaksonen include University of Tampere & Helsinki University of Technology.
Papers
More filters
Journal ArticleDOI
Electrochemical resolution of 15 oxidation states for monolayer protected gold nanoparticles.
TL;DR: The first observation of 15 voltammetric quantized charging peaks for a solution of hexanethiol-capped gold nanoparticles (so-called monolayer protected clusters MPCs) at room temperature is reported where the variation in peak spacing with increasing charge stored in the metal core is discussed in terms of MPC capacitance.
Journal ArticleDOI
Biocompatibility of Thermally Hydrocarbonized Porous Silicon Nanoparticles and their Biodistribution in Rats
Luis M. Bimbo,Mirkka Sarparanta,Hélder A. Santos,Anu J. Airaksinen,Ermei Mäkilä,Timo Laaksonen,Leena Peltonen,Vesa-Pekka Lehto,Jouni Hirvonen,Jarno Salonen +9 more
TL;DR: Results show that thermally hydrocarbonized porous silicon (THCPSi) nanoparticles did not induce any significant toxicity, oxidative stress, or inflammatory response in Caco-2 and RAW 264.7 macrophage cells.
Journal ArticleDOI
Gold nanoparticles enable selective light-induced contents release from liposomes.
Lauri Paasonen,Timo Laaksonen,Christoffer Johans,Marjo Yliperttula,Kyösti Kontturi,Arto Urtti +5 more
TL;DR: A novel proof of principle demonstration for contents release from liposomes that can be selectively activated by light irradiation is presented, and triggered contents release was triggered by UV light-induced heating of the gold nanoparticles.
Journal ArticleDOI
Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content
Zachary J. Smith,Changwon Lee,Tatu Rojalin,Randy P. Carney,Sidhartha Hazari,Alisha Knudson,Kit S. Lam,Heikki Saari,Elisa Lazaro Ibanez,Tapani Viitala,Timo Laaksonen,Marjo Yliperttula,Sebastian Wachsmann-Hogiu +12 more
TL;DR: The first to indicate that exosome subpopulations are shared among cell types, suggesting distributed exosomes functionality is indicated, and the major sources of spectral variation were in cholesterol content, relative expression of phospholipids to cholesterol, and surface protein expression.
Journal ArticleDOI
Nanofibrillar cellulose films for controlled drug delivery
TL;DR: The results indicate that the nanofibrillar cellulose is a highly promising new material for sustained release drug delivery applications.