T
Timo Strünker
Researcher at University of Münster
Publications - 49
Citations - 2574
Timo Strünker is an academic researcher from University of Münster. The author has contributed to research in topics: Sperm & Sperm motility. The author has an hindex of 20, co-authored 42 publications receiving 2134 citations. Previous affiliations of Timo Strünker include Max Planck Society & Forschungszentrum Jülich.
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Journal ArticleDOI
The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm
Timo Strünker,Normann Goodwin,Christoph Brenker,Nachiket D. Kashikar,Nachiket D. Kashikar,Ingo Weyand,Reinhard Seifert,U. Benjamin Kaupp +7 more
TL;DR: It is found that both progesterone and alkaline pH stimulate a rapid Ca2+ influx with almost no latency, incompatible with a signalling pathway involving metabotropic receptors and second messengers.
Journal ArticleDOI
Fast manipulation of cellular cAMP level by light in vivo
Saskia Schröder-Lang,Martin Schwärzel,Reinhard Seifert,Timo Strünker,Suneel Kateriya,Jens Looser,Masakatsu Watanabe,U. Benjamin Kaupp,Peter Hegemann,Georg Nagel +9 more
TL;DR: The flagellate Euglena gracilis contains a photoactivated adenylyl cyclase (PAC), consisting of the flavoproteins PACα and PACβ, providing a powerful tool for light-induced manipulation of cAMP in animal cells.
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The CatSper channel: a polymodal chemosensor in human sperm
Christoph Brenker,Normann Goodwin,Ingo Weyand,Nachiket D. Kashikar,M. Naruse,M. Krahling,Astrid Müller,Ulrich Benjamin Kaupp,Timo Strünker +8 more
TL;DR: The results contest current concepts of Ca2+ signalling by GPCR and cAMP in mammalian sperm: ligands thought to activate metabotropic pathways, in fact, act via a common ionotropic mechanism.
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Molecular and functional characterization of an octopamine receptor from honeybee (Apis mellifera) brain.
TL;DR: The cloning and functional characterization of the first octopamine receptor from the honeybee, Apis mellifera, are reported, suggesting that this octopamines receptor is involved in the processing of sensory inputs, antennal motor outputs and higher‐order brain functions.
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A family of octapamine receptors that specifically induce cyclic AMP production or Ca2+ release in Drosophila melanogaster
TL;DR: The functional characterization of two genes from Drosophila melanogaster that encode unique receptors that display signature properties of native octopamine receptors are described.