T
Tina Mainka
Researcher at Charité
Publications - 53
Citations - 1093
Tina Mainka is an academic researcher from Charité. The author has contributed to research in topics: Medicine & Hyperalgesia. The author has an hindex of 14, co-authored 45 publications receiving 778 citations. Previous affiliations of Tina Mainka include University of Hamburg & Ruhr University Bochum.
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Journal ArticleDOI
Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles.
R. Baron,Christoph Maier,Nadine Attal,Andreas Binder,Didier Bouhassira,Giorgio Cruccu,Nanna B. Finnerup,Maija Haanpää,Per Hansson,Per Hansson,Philipp Hüllemann,Troels S. Jensen,Rainer Freynhagen,Jeffrey D. Kennedy,Walter Magerl,Tina Mainka,Tina Mainka,Maren Reimer,Andrew S.C. Rice,Märta Segerdahl,Märta Segerdahl,Jordi Serra,Søren H. Sindrup,Claudia Sommer,Thomas R. Tölle,Jan Vollert,Jan Vollert,Rolf-Detlef Treede +27 more
TL;DR: A new approach of subgrouping patients with peripheral neuropathic pain of different etiologies according to intrinsic sensory profiles is presented, which may be related to pathophysiological mechanisms and may be useful in clinical trial design to enrich the study population for treatment responders.
Journal ArticleDOI
Presence of hyperalgesia predicts analgesic efficacy of topically applied capsaicin 8% in patients with peripheral neuropathic pain.
Tina Mainka,Tina Mainka,Nathalie M. Malewicz,R. Baron,Elena K. Enax-Krumova,Rolf-Detlef Treede,Christoph Maier +6 more
TL;DR: A positive correlation between pain relief and increase in the warmth detection threshold (WDT) is hypothesized, indicating loss of C‐fibre function, and higher response rates in patients with preserved C‐ fibrre function or heat hyperalgesia before application.
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Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile.
Aoibhinn McDonnell,Betsy R. Schulman,Zahid Ali,Sulayman D. Dib-Hajj,Fiona Brock,Sonia Cobain,Tina Mainka,Jan Vollert,Sanela Tarabar,Stephen G. Waxman +9 more
TL;DR: Inherited erythromelalgia, the first human pain syndrome linked to voltage-gated sodium channels, is widely regarded as a genetic model of human pain, and the importance of characterizing the pain phenotype in individuals before undertaking clinical trials is indicated.
Journal ArticleDOI
Who is healthy?: Aspects to consider when including healthy volunteers in QST-based studies- a consensus statement by the EUROPAIN and NEUROPAIN consortia
Janne Gierthmühlen,Elena K. Enax-Krumova,Nadine Attal,Didier Bouhassira,Giorgio Cruccu,Nanna B. Finnerup,Maija Haanpää,Per Hansson,Troels S. Jensen,Rainer Freynhagen,Jeffrey D. Kennedy,Tina Mainka,Andrew S.C. Rice,Märta Segerdahl,Søren H. Sindrup,Jordi Serra,Thomas R. Tölle,Rolf-Detlef Treede,Ralf Baron,Christoph Maier +19 more
TL;DR: Suggestions for inclusion criteria of healthy volunteers into QST-based trials describe a 2-level approach including standardized questionnaires enabling the collection of relevant information on sociodemographic data, medical history, current health status, coping strategies in dealing with pain, and the motivation of the volunteer to participate in the study.
Journal ArticleDOI
Quality assurance for Quantitative Sensory Testing laboratories: development and validation of an automated evaluation tool for the analysis of declared healthy samples.
Jan Vollert,Tina Mainka,Ralf Baron,Elena K. Enax-Krumova,Philipp Hüllemann,Christoph Maier,Doreen B. Pfau,Thomas R. Tölle,Rolf-Detlef Treede +8 more
TL;DR: Sensitivity and specificity of detecting inclusion errors and reasons for measuring errors were assessed in 431 healthy subjects and 833 patients with neuropathic pain syndromes from the German Research Network on Neuropathic Pain database and underlines the usefulness and validity of a tool for assessing samples of healthy subjects in quality assurance of QST laboratories using the DFNS protocol.