J
Jeffrey D. Kennedy
Researcher at Eli Lilly and Company
Publications - 11
Citations - 986
Jeffrey D. Kennedy is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Chronic pain & Hyperalgesia. The author has an hindex of 11, co-authored 11 publications receiving 775 citations.
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Journal ArticleDOI
Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles.
R. Baron,Christoph Maier,Nadine Attal,Andreas Binder,Didier Bouhassira,Giorgio Cruccu,Nanna B. Finnerup,Maija Haanpää,Per Hansson,Per Hansson,Philipp Hüllemann,Troels S. Jensen,Rainer Freynhagen,Jeffrey D. Kennedy,Walter Magerl,Tina Mainka,Tina Mainka,Maren Reimer,Andrew S.C. Rice,Märta Segerdahl,Märta Segerdahl,Jordi Serra,Søren H. Sindrup,Claudia Sommer,Thomas R. Tölle,Jan Vollert,Jan Vollert,Rolf-Detlef Treede +27 more
TL;DR: A new approach of subgrouping patients with peripheral neuropathic pain of different etiologies according to intrinsic sensory profiles is presented, which may be related to pathophysiological mechanisms and may be useful in clinical trial design to enrich the study population for treatment responders.
Journal ArticleDOI
One night of total sleep deprivation promotes a state of generalized hyperalgesia: A surrogate pain model to study the relationship of insomnia and pain
Sigrid Schuh-Hofer,Sigrid Schuh-Hofer,Rachel Wodarski,Doreen B. Pfau,Ombretta Caspani,Walter Magerl,Jeffrey D. Kennedy,Rolf-Detlef Treede +7 more
TL;DR: Findings show that a single night of TSD is able to induce generalized hyperalgesia and to increase State Anxiety scores, and TSD selectively modulated nociception, since detection thresholds of non‐nociceptive modalities remained unchanged.
Journal ArticleDOI
Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations
Nick Andrews,Alban Latremoliere,Allan I. Basbaum,Jeffrey S. Mogil,Frank Porreca,Andrew S.C. Rice,Clifford J. Woolf,Gillian L. Currie,Robert H. Dworkin,James C. Eisenach,Scott R. Evans,Jennifer S. Gewandter,Tony D. Gover,Hermann O. Handwerker,Wenlong Huang,Smriti Iyengar,Mark P. Jensen,Jeffrey D. Kennedy,Nancy Lee,Jon D. Levine,Katie Lidster,Ian Machin,Michael P. McDermott,Stephen B. McMahon,Theodore J. Price,Sarah E. Ross,Grégory Scherrer,Rebecca P. Seal,Emily S. Sena,Elizabeth A. Silva,Laura Stone,Camilla I. Svensson,Dennis C. Turk,Garth Whiteside +33 more
TL;DR: To achieve the goal of finding effective new treatments for patients with pain, the pain field needs to deal with these challenging issues, and greater transparency of reporting should be driven by scientists, journal editors, reviewers, and grant funders.
Journal ArticleDOI
Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study.
Rachel Wodarski,Rachel Wodarski,Ada Delaney,Camilla Ultenius,Rosie Morland,Nick Andrews,Catherine Baastrup,Luke A. Bryden,Ombretta Caspani,Thomas Christoph,Natalie J. Gardiner,Wenlong Huang,Jeffrey D. Kennedy,Suguru Koyama,Dominic L. Li,Marcin Ligocki,Annika Lindsten,Ian Machin,Anton Pekcec,A. Robens,Sanziana M. Rotariu,Sabrina Voß,Märta Segerdahl,Märta Segerdahl,Carina Stenfors,Camilla I. Svensson,Rolf-Detlef Treede,Katsuhiro Uto,Kazumi Yamamoto,Kris Rutten,Andrew S.C. Rice +30 more
TL;DR: This unique multicentre approach provided high-quality evidence evaluating suppressed burrowing as robust and reproducible, supporting its use as tool to infer the global effect of pain on rodents.
Journal ArticleDOI
Who is healthy?: Aspects to consider when including healthy volunteers in QST-based studies- a consensus statement by the EUROPAIN and NEUROPAIN consortia
Janne Gierthmühlen,Elena K. Enax-Krumova,Nadine Attal,Didier Bouhassira,Giorgio Cruccu,Nanna B. Finnerup,Maija Haanpää,Per Hansson,Troels S. Jensen,Rainer Freynhagen,Jeffrey D. Kennedy,Tina Mainka,Andrew S.C. Rice,Märta Segerdahl,Søren H. Sindrup,Jordi Serra,Thomas R. Tölle,Rolf-Detlef Treede,Ralf Baron,Christoph Maier +19 more
TL;DR: Suggestions for inclusion criteria of healthy volunteers into QST-based trials describe a 2-level approach including standardized questionnaires enabling the collection of relevant information on sociodemographic data, medical history, current health status, coping strategies in dealing with pain, and the motivation of the volunteer to participate in the study.