T
To Nam Tham
Researcher at Pasteur Institute
Publications - 32
Citations - 2349
To Nam Tham is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Gene & Septin. The author has an hindex of 21, co-authored 32 publications receiving 2202 citations. Previous affiliations of To Nam Tham include French Institute of Health and Medical Research & St. Jude Children's Research Hospital.
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Journal ArticleDOI
Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system.
Françoise Lazarini,To Nam Tham,Philippe Casanova,Fernando Arenzana-Seisdedos,Monique Dubois-Dalcq +4 more
TL;DR: By modulating cell signaling and survival during neuroinflammation, SDF‐1 may also play a role in the pathogenesis of brain tumors, experimental allergic encephalitis, and the nervous system dysfunction associated with acquired immunodeficiency syndrome.
Journal ArticleDOI
Histone modifications induced by a family of bacterial toxins
Melanie Hamon,Eric Batsché,Béatrice Regnault,To Nam Tham,Stephanie Seveau,Christian Muchardt,Pascale Cossart +6 more
TL;DR: Control of epigenetic regulation emerges here as an unsuspected function shared by several bacterial toxins, highlighting a common strategy used by intracellular and extracellular pathogens to modulate the host response early during infection.
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Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures
Serge Mostowy,Serge Mostowy,Serge Mostowy,Matteo Bonazzi,Matteo Bonazzi,Matteo Bonazzi,Melanie Hamon,Melanie Hamon,Melanie Hamon,To Nam Tham,To Nam Tham,To Nam Tham,Adeline Mallet,Mickaël Lelek,Mickaël Lelek,Edith Gouin,Edith Gouin,Edith Gouin,Caroline Demangel,Roland Brosch,Christophe Zimmer,Christophe Zimmer,Anna Sartori,Makoto Kinoshita,Marc Lecuit,Marc Lecuit,Marc Lecuit,Pascale Cossart,Pascale Cossart,Pascale Cossart +29 more
TL;DR: It is reported that septin assemblies are recruited to different bacteria that polymerize actin, and it is observed that intracytosolic Shigella either become compartmentalized in septin cage-like structures or form actin tails.
Journal ArticleDOI
A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors
M. Dziembowska,To Nam Tham,Pierre Lau,Sandrine Vitry,Françoise Lazarini,Monique Dubois-Dalcq +5 more
TL;DR: The present study shows that signaling of CXCR4 receptor by the chemokine CXCL12 regulates survival and migration of neural precursors as well as oligodendrocyte progenitors (OP) during embryonic and postnatal CNS development.
Journal ArticleDOI
A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
Alice Lebreton,Alice Lebreton,Alice Lebreton,Goran Lakisic,Viviana Job,Lauriane Fritsch,To Nam Tham,To Nam Tham,To Nam Tham,Ana Camejo,Pierre-Jean Matteï,Béatrice Regnault,Marie-Anne Nahori,Marie-Anne Nahori,Marie-Anne Nahori,Didier Cabanes,Alexis Gautreau,Slimane Ait-Si-Ali,Andréa Dessen,Pascale Cossart,Pascale Cossart,Pascale Cossart,Hélène Bierne,Hélène Bierne,Hélène Bierne +24 more
TL;DR: The LntA-BAHD1 interplay may modulate IFN-λ−mediated immune response to control bacterial colonization of the host.