V
Viviana Job
Researcher at University of Grenoble
Publications - 38
Citations - 1720
Viviana Job is an academic researcher from University of Grenoble. The author has contributed to research in topics: Type three secretion system & Periplasmic space. The author has an hindex of 19, co-authored 35 publications receiving 1533 citations. Previous affiliations of Viviana Job include French Alternative Energies and Atomic Energy Commission & Centre national de la recherche scientifique.
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Journal ArticleDOI
Penicillin Binding Proteins: key players in bacterial cell cycle and drug resistance processes
TL;DR: Structural, functional and biological features of penicillin-binding proteins, albeit having initially been identified several decades ago, are now being aggressively pursued as highly attractive targets for the development of novel antibiotherapies.
Journal ArticleDOI
A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
Alice Lebreton,Alice Lebreton,Alice Lebreton,Goran Lakisic,Viviana Job,Lauriane Fritsch,To Nam Tham,To Nam Tham,To Nam Tham,Ana Camejo,Pierre-Jean Matteï,Béatrice Regnault,Marie-Anne Nahori,Marie-Anne Nahori,Marie-Anne Nahori,Didier Cabanes,Alexis Gautreau,Slimane Ait-Si-Ali,Andréa Dessen,Pascale Cossart,Pascale Cossart,Pascale Cossart,Hélène Bierne,Hélène Bierne,Hélène Bierne +24 more
TL;DR: The LntA-BAHD1 interplay may modulate IFN-λ−mediated immune response to control bacterial colonization of the host.
Journal ArticleDOI
Membrane targeting and pore formation by the type III secretion system translocon.
TL;DR: Recent advances on the biochemical and structural characterization of the proteins involved in translocon formation, as well as their participation in the modification of intracellular signalling pathways upon infection are discussed.
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Biogenesis, Regulation, and Targeting of the Type III Secretion System
TL;DR: Recent advances in the structural characterization of T3 SS proteins from a number of bacteria are reported, and an overview of recently identified small molecule T3SS inhibitors that could potentially be explored for novel antibacterial development is provided.
Journal ArticleDOI
Active site restructuring regulates ligand recognition in class A penicillin-binding proteins
Pauline Macheboeuf,Anne Marie Di Guilmi,Viviana Job,Thierry Vernet,Otto Dideberg,Andréa Dessen +5 more
TL;DR: The structure of PBP1b* complexed with beta-lactam antibiotics reveals that ligand recognition requires a conformational modification involving conserved elements within the cleft, and suggest how class A PBPs may become activated as novel peptidoglycan synthesis becomes necessary during the cell division process.