T
Todd E. Peterson
Researcher at Vanderbilt University Medical Center
Publications - 114
Citations - 2810
Todd E. Peterson is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Detector & Collimator. The author has an hindex of 26, co-authored 111 publications receiving 2588 citations. Previous affiliations of Todd E. Peterson include Indiana University & University of Pennsylvania.
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Journal ArticleDOI
MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL
Conor C. Lynch,Atsuya Hikosaka,Heath B. Acuff,Michelle D. Martin,Noriyasu Kawai,Rakesh K. Singh,Tracy Vargo-Gogola,Jennifer L. Begtrup,Todd E. Peterson,Barbara Fingleton,Tomoyuki Shirai,Lynn M. Matrisian,Mitsuru Futakuchi,Mitsuru Futakuchi +13 more
TL;DR: It is suggested that inhibition of MMP-7 will have therapeutic benefit in the treatment of prostate cancer-induced osteolysis.
Journal ArticleDOI
Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats
Carrie K. Jones,Ashley E. Brady,Albert A. Davis,Zixiu Xiang,Michael Bubser,Mohammed N. Tantawy,Alexander S. Kane,Thomas M. Bridges,J. Phillip Kennedy,Stefania Risso Bradley,Todd E. Peterson,M. Sib Ansari,Ronald M. Baldwin,Robert M. Kessler,Ariel Y. Deutch,James J. Lah,Allan I. Levey,Craig W. Lindsley,P. Jeffrey Conn +18 more
TL;DR: Characterization of a novel highly selective agonist for the M1 receptor with no agonist activity at any of the other mAChR subtypes, termed TBPB, and data suggest that selective activation of M1 may provide a novel approach for the treatment of symptoms associated with schizophrenia and Alzheimer's disease.
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SPECT detectors: the Anger Camera and beyond.
TL;DR: The key performance properties of SPECT detectors and survey developments in both scintillator and semiconductor detectors and their readouts are discussed with an eye toward some of the practical issues at least in part responsible for the continuing prevalence of the Anger Camera in the clinic.
Journal Article
Voxel-Based Mouse and Rat Models for Internal Dose Calculations
TL;DR: The segmented, voxel-based models developed here can be used for external dose calculations as well and will be useful in determining the dose to organs for mice and rats similar in size to those studied here.
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SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays
Hyunki Kim,Lars R. Furenlid,Michael J. Crawford,Donald W. Wilson,H. Bradford Barber,Todd E. Peterson,William C. J. Hunter,Zhonglin Liu,James M. Woolfenden,Harrison H. Barrett +9 more
TL;DR: The first full single-photon emission computed tomography (SPECT) imager to exploit eight compact high-intrinsic-resolution cadmium zinc telluride (CZT) detectors, called SemiSPECT, has been completed and line-phantom images are presented to visualize the spatial resolution provided by Semi SPECT.