T
Toju Tanaka
Publications - 7
Citations - 310
Toju Tanaka is an academic researcher. The author has contributed to research in topics: Hunter syndrome & Enzyme replacement therapy. The author has an hindex of 4, co-authored 5 publications receiving 270 citations.
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Journal ArticleDOI
Japan Elaprase Treatment (JET) study: idursulfase enzyme replacement therapy in adult patients with attenuated Hunter syndrome (Mucopolysaccharidosis II, MPS II).
Torayuki Okuyama,Akemi Tanaka,Yasuyuki Suzuki,Hiroyuki Ida,Toju Tanaka,Gerald F. Cox,Gerald F. Cox,Yoshikatsu Eto,Tadao Orii +8 more
TL;DR: Idursulfase treatment appears to be safe and effective in adult Japanese patients with attenuated MPS II and advanced disease, comparable to those of prior studies that enrolled predominantly pediatric, Caucasian, and less ill patients.
Journal ArticleDOI
Long-term efficacy of hematopoietic stem cell transplantation on brain involvement in patients with mucopolysaccharidosis type II: a nationwide survey in Japan.
Akemi Tanaka,Torayuki Okuyama,Yasuyuki Suzuki,Norio Sakai,Hiromitsu Takakura,Tomo Sawada,Toju Tanaka,Takanobu Otomo,Toya Ohashi,Mika Ishige-Wada,Hiromasa Yabe,Toshihiro Ohura,Nobuhiro Suzuki,Koji Kato,Souichi Adachi,Ryoji Kobayashi,Hideo Mugishima,Shunichi Kato +17 more
TL;DR: HSCT showed effectiveness towards brain or heart involvement, when performed before signs of brain atrophy or valvular regurgitation appear, and it is considered HSCT is worthwhile in early stages of the disease for patients with MPS II.
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Newborn screening for Pompe disease in Japan
Eri Oda,Toju Tanaka,Ohsuke Migita,Motomichi Kosuga,Masaru Fukushi,Toshika Okumiya,Makiko Osawa,Torayuki Okuyama +7 more
TL;DR: The low false-positive rate suggests that NBS for Pompe disease is feasible in Japan, and the comparatively high frequency of pseudodeficiency allele makes NBSfor Pompe disease complicated in Taiwan.
Journal ArticleDOI
Clinical manifestation and long‐term outcome of citrin deficiency: Report from a nationwide study in Japan
Jun Kido,Johannes Häberle,Keishin Sugawara,Toju Tanaka,Masayoshi Nagao,Takaaki Sawada,Yoichi Wada,Chikahiko Numakura,Kei Murayama,Yoriko Watanabe,Kanako Kojima-Ishii,Hideo Sasai,Kiyotaka Kosugiyama,Kimitoshi Nakamura +13 more
TL;DR: It is suggested that early intervention including a low carbohydrate diet and MCT supplementation can be associated with improved clinical course and long‐term outcome in Japanese patients with citrin deficiency.
Journal ArticleDOI
Monozygotic twins of Smith-Magenis syndrome.
TL;DR: The first reported case of monozygotic twins with Smith–Magenis syndrome, born to a 26-year-old Japanese G2P1-3 woman with no previous medical problems, are document.