T
Tomo Sawada
Researcher at Osaka City University
Publications - 3
Citations - 147
Tomo Sawada is an academic researcher from Osaka City University. The author has contributed to research in topics: Cytotoxic T cell & Retrospective cohort study. The author has an hindex of 3, co-authored 3 publications receiving 128 citations.
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Long-term efficacy of hematopoietic stem cell transplantation on brain involvement in patients with mucopolysaccharidosis type II: a nationwide survey in Japan.
Akemi Tanaka,Torayuki Okuyama,Yasuyuki Suzuki,Norio Sakai,Hiromitsu Takakura,Tomo Sawada,Toju Tanaka,Takanobu Otomo,Toya Ohashi,Mika Ishige-Wada,Hiromasa Yabe,Toshihiro Ohura,Nobuhiro Suzuki,Koji Kato,Souichi Adachi,Ryoji Kobayashi,Hideo Mugishima,Shunichi Kato +17 more
TL;DR: HSCT showed effectiveness towards brain or heart involvement, when performed before signs of brain atrophy or valvular regurgitation appear, and it is considered HSCT is worthwhile in early stages of the disease for patients with MPS II.
Journal ArticleDOI
Intracerebral cell transplantation therapy for murine GM1 gangliosidosis
Tomo Sawada,Akemi Tanaka,Katsumi Higaki,Ayumi Takamura,Eiji Nanba,Toshiyuki Seto,Mitsuyo Maeda,Etsuko Yamaguchi,Junichiro Matsuda,T. Yamano +9 more
TL;DR: To achieve sufficient long-term effects on the brain, a method of steering the immune response away from cytotoxic responses or of inducing tolerance to the products of therapeutic genes must be developed.
Journal ArticleDOI
Mutant alleles associated with late-onset ornithine transcarbamylase deficiency in male patients have recurrently arisen and have been retained in some populations
Sanae Numata,Yoshiro Koda,Kenji Ihara,Tomo Sawada,Yoshiyuki Okano,Toshinobu Matsuura,Fumio Endo,Han Wook Yoo,José Antonio Arranz,Vicente Rubio,Bendicht Wermuth,Nicholas Ah Mew,Mendel Tuchman,Jason Pinner,Edwin P. Kirk,Makoto Yoshino +15 more
TL;DR: Results indicate that the p.R40H mutation has arisen recurrently in all populations studied, although there is evidence for a founder effect in Japan, with most cases probably sharing a common origin, and to a lesser extent in subjects of European ancestry (HT3).