T
Tom Volpe
Researcher at Cold Spring Harbor Laboratory
Publications - 12
Citations - 4505
Tom Volpe is an academic researcher from Cold Spring Harbor Laboratory. The author has contributed to research in topics: RNA interference & Saccharomyces cerevisiae. The author has an hindex of 12, co-authored 12 publications receiving 4380 citations. Previous affiliations of Tom Volpe include State University of New York System & Watson School of Biological Sciences.
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Journal ArticleDOI
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi.
Tom Volpe,Catherine A. Kidner,Ira M. Hall,Ira M. Hall,Grace Teng,Grace Teng,Shiv I. S. Grewal,Robert A. Martienssen +7 more
TL;DR: It is proposed that double-stranded RNA arising from centromeric repeats targets formation and maintenance of heterochromatin through RNAi.
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Patterns of gene action in plant development revealed by enhancer trap and gene trap transposable elements.
Venkatesan Sundaresan,Patricia Springer,Tom Volpe,Samuel Haward,Samuel Haward,Jonathan D. G. Jones,Caroline Dean,Hong Ma,Robert A. Martienssen +8 more
TL;DR: The development of an efficient insertional mutagenesis system in Arabidopsis that permits identification of genes by their patterns of expression during development and suggests that the identification and cloning ofArabidopsis genes expressed in any developmental process is feasible using this system.
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Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth
Gefeng Zhu,Paul T. Spellman,Tom Volpe,Tom Volpe,Patrick O. Brown,David Botstein,Trisha N. Davis,Bruce Futcher +7 more
TL;DR: The fkh1 fkh2 mutant displays a constitutive pseudohyphal morphology, indicating that Fkh1 and Fkh2 may help control the switch to this mode of growth, and indicating that a cascade of transcription factors operates late in the cell cycle.
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RNA interference is required for normal centromere function in fission yeast.
Tom Volpe,Vera Schramke,Georgina L. Hamilton,Sharon A. White,Grace Teng,Robert A. Martienssen,Robin C. Allshire +6 more
TL;DR: Analysis of dg transcription indicates that csp mutants, previously shown to abrogate centromere silencing and chromosome segregation, are also defective in the regulation of non-coding centromeric RNAs.
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Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast.
TL;DR: It is found that stimulation of the Ras/cAMP pathway represses expression of CLN1, CLN2 and co-regulated genes, inhibiting Start, which helps explain the increase in critical size when cells are shifted from poor to rich medium.