T
Tomas Cajka
Researcher at Academy of Sciences of the Czech Republic
Publications - 112
Citations - 8891
Tomas Cajka is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Mass spectrometry & Lipidomics. The author has an hindex of 42, co-authored 94 publications receiving 6519 citations. Previous affiliations of Tomas Cajka include Institute of Chemical Technology in Prague & University of California.
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Journal ArticleDOI
MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis.
Hiroshi Tsugawa,Tomas Cajka,Tobias Kind,Yan Ma,Brendan T. Higgins,Kazutaka Ikeda,Mitsuhiro Kanazawa,Jean S. VanderGheynst,Oliver Fiehn,Masanori Arita +9 more
TL;DR: For a reversed-phase LC-MS/MS analysis of nine algal strains, MS-DIAL using an enriched LipidBlast library identified 1,023 lipid compounds, highlighting the chemotaxonomic relationships between theAlgal strains.
Journal ArticleDOI
Toward Merging Untargeted and Targeted Methods in Mass Spectrometry-Based Metabolomics and Lipidomics.
TL;DR: This work focuses on the application of mass spectrometry to the treatment of metabolomics and Lipidomics with a focus on the characterization of the role of phosphorous in the biosynthetic pathway.
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Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry
Tomas Cajka,Oliver Fiehn +1 more
TL;DR: This review focuses on state of the art in LC-MS-based lipidomics, covering all the steps of global lipidomic profiling, and concludes that phospholipids followed by sphingomyelins, di- and tri-acylglycerols, and ceramides were the most frequently targeted lipid species.
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Hydrogen Rearrangement Rules: Computational MS/MS Fragmentation and Structure Elucidation Using MS-FINDER Software
Hiroshi Tsugawa,Tobias Kind,Ryo Nakabayashi,Daichi Yukihira,Wataru Tanaka,Tomas Cajka,Kazuki Saito,Oliver Fiehn,Oliver Fiehn,Masanori Arita,Masanori Arita +10 more
TL;DR: Nine rules of hydrogen rearrangement during bond cleavages in low-energy collision-induced dissociation (CID) are proposed based on the classic even-electron rule and cover heteroatoms and multistage fragmentation.
Journal ArticleDOI
A lipidome atlas in MS-DIAL 4.
Hiroshi Tsugawa,Kazutaka Ikeda,Mikiko Takahashi,Aya O. Satoh,Yoshifumi Mori,Haruki Uchino,Nobuyuki Okahashi,Yutaka Yamada,Ipputa Tada,Paolo Bonini,Yasuhiro Higashi,Yozo Okazaki,Zhiwei Zhou,Zheng-Jiang Zhu,Jeremy P. Koelmel,Jeremy P. Koelmel,Tomas Cajka,Oliver Fiehn,Kazuki Saito,Masanori Arita,Makoto Arita,Makoto Arita +21 more
TL;DR: A comprehensive lipidome atlas with retention time, collision cross-section and tandem mass spectrometry information is presented and mass spectral fragmentations of lipids across 117 lipid subclasses are presented in a lipidomeAtlas.