T
Tomasz Szkudelski
Researcher at University of Agriculture, Faisalabad
Publications - 75
Citations - 6166
Tomasz Szkudelski is an academic researcher from University of Agriculture, Faisalabad. The author has contributed to research in topics: Insulin & Lipolysis. The author has an hindex of 25, co-authored 72 publications receiving 5641 citations. Previous affiliations of Tomasz Szkudelski include Academy of Sciences of the Czech Republic & University of Life Sciences in Poznań.
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Journal Article
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas.
TL;DR: The cytotoxic action of both these diabetogenic agents is mediated by reactive oxygen species, however, the source of their generation is different in the case of alloxan and streptozotocin.
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What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol
Ole Vang,Nihal Ahmad,Clifton A. Baile,Joseph A. Baur,Karen Brown,Anna Csiszar,Dipak K. Das,Dominique Delmas,Carmem Gottfried,Hung Yun Lin,Qing-Yong Ma,Partha Mukhopadhyay,Namasivayam Nalini,John M. Pezzuto,Tristan Richard,Yogeshwer Shukla,Young-Joon Surh,Thomas Szekeres,Tomasz Szkudelski,Thomas Walle,Joseph M. Wu +20 more
TL;DR: The published evidence is not sufficiently strong to justify a recommendation for the administration of resveratrol to humans, beyond the dose which can be obtained from dietary sources, and animal data are promising in prevention of various cancer types, coronary heart diseases and diabetes which strongly indicate the need for human clinical trials.
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Resveratrol, obesity and diabetes.
TL;DR: New data indicate that in diabetic rats, resveratrol is able to reduce hyperglycemia and point to the potential possibility of use of resver atrol in preventing and/or treating both obesity and diabetes.
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Streptozotocin-nicotinamide-induced diabetes in the rat. Characteristics of the experimental model.
TL;DR: In vitro studies demonstrated that the insulin-secretory response to glucose is attenuated in STZ–NA-induced diabetic rats compared with control animals, and this model of diabetes is useful in studies of different aspects of diabetes.
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Resveratrol and diabetes: from animal to human studies
TL;DR: Results show that resveratrol holds great potential to treat diabetes and would be useful to support conventional therapy, and anti-oxidant andanti-inflammatory effects of this compound were shown to be also involved in its action in diabetic animals.