T
Tord Labuda
Researcher at Leo Pharma
Publications - 25
Citations - 1224
Tord Labuda is an academic researcher from Leo Pharma. The author has contributed to research in topics: T cell & Cytotoxic T cell. The author has an hindex of 14, co-authored 25 publications receiving 1145 citations. Previous affiliations of Tord Labuda include University of Copenhagen & Institute of Molecular Biotechnology.
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Journal ArticleDOI
Jun Turnover Is Controlled Through JNK-Dependent Phosphorylation of the E3 Ligase Itch
Min Gao,Tord Labuda,Tord Labuda,Tord Labuda,Ying Xia,Ying Xia,Ying Xia,Ewen Gallagher,Ewen Gallagher,Ewen Gallagher,Deyu Fang,Deyu Fang,Deyu Fang,Yun Cai Liu,Yun Cai Liu,Yun Cai Liu,Michael Karin,Michael Karin,Michael Karin +18 more
TL;DR: It is found that extracellular stimuli also modulate protein turnover by regulating the activity of an E3 ligase by means of its phosphorylation.
Journal ArticleDOI
IKKβ Is Required for Peripheral B Cell Survival and Proliferation
TL;DR: It is found that the loss of IKKβ results in a dramatic reduction in all peripheral B cell subsets due to associated defects in cell survival, consistent with a failure to mount effective Ab responses to T cell-dependent and independent Ags.
Journal ArticleDOI
Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma.
Thorbjørn Krejsgaard,Claudia S. Vetter-Kauczok,Anders Woetmann,Paola Lovato,Tord Labuda,Karsten W. Eriksen,Qunzhou Zhang,Jürgen C. Becker,Niels Ødum +8 more
TL;DR: It is shown that malignant CTCL T cells spontaneously produce the potent angiogenic protein, vascular endothelial growth factor (VEGF), which is promoted by aberrant activation of Jak3 and the JNKs.
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Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling
David Adrian Ewald,David Adrian Ewald,David Adrian Ewald,Shinji Noda,Margeaux Oliva,Thomas Litman,Thomas Litman,Saeko Nakajima,Xuan Li,Hui Xu,Christopher T. Workman,Peter Scheipers,Naila Svitacheva,Tord Labuda,James G. Krueger,Mayte Suárez-Fariñas,Mayte Suárez-Fariñas,Kenji Kabashima,Kenji Kabashima,Emma Guttman-Yassky,Emma Guttman-Yassky +20 more
TL;DR: This article evaluated the transcriptomic profiles of 6 common murine models and determine how they relate to human AD skin using microarrays and quantitative RT-PCR on biopsy specimens from NC/Nga, flaky tail, flg-mutated, ovalbumin-challenged, oxazolone-challenced, and IL-23-injected mice.
Journal ArticleDOI
Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins
Anders Woetmann,Paola Lovato,Paola Lovato,Karsten W. Eriksen,Karsten W. Eriksen,Thorbjørn Krejsgaard,Thorbjørn Krejsgaard,Tord Labuda,Tord Labuda,Qian Zhang,Anne-Merethe Mathiesen,Anne-Merethe Mathiesen,Carsten Geisler,Arne Svejgaard,Mariusz A. Wasik,Niels Ødum,Niels Ødum +16 more
TL;DR: It is demonstrated that SE triggers a bidirectional cross talk between nonmalignant T cells and malignant CTCL cells that promotes growth of the malignant cells.