Torstein Tengs

TL;DR: It is shown that microreactor-based pyrosequencing can detect rare cancer-associated sequence variations by independent and parallel sampling of multiple representatives of a given DNA fragment and can thereby facilitate accurate molecular diagnosis of heterogeneous cancer specimens and enable patient selection for targeted cancer therapies.

TL;DR: A real-time PCR-based assay is developed that permits rapid and specific identification of Pfiesteria complex species in culture and heterogeneous environmental water samples and will be useful for many other applications, including adaptation for field-based technology.

TL;DR: Analyses of SSU rDNA from the plastid and the nuclear genome of these dinoflagellate species indicate that they have acquired their plastids via endosymbiosis of a haptophyte, and distance, parsimony, and maximum-likelihood phylogenetic analyses of plastido rRNA gene sequences place the three species within the haptophical clade.

TL;DR: A sequencing strategy directed by heteroduplex mobility assay-directed sequence discovery is broadly applicable, and may be adapted for the detection of genomic sequence data of other novel or nonculturable organisms in complex assemblages.

TL;DR: The development and validation of a suite of real‐time polymerase chain reaction (PCR) assays for species associated with fish kill events in Japanese, European, Canadian, and U.S. coastal waters and phylogenetic analyses to determine the relationship between these species were performed.